| Document Date: 2009-03-31 15:46:55
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City Hobart / Philadelphia / Wayne / / Company AEs / AMP / Shire US Inc. / MALLINCKRODT INC. / Ames / / Country United States / / Event FDA Phase / / IndustryTerm food / / MedicalCondition Polycythemia Vera / myeloproliferative disorder / lymphoma / Chest Pain / headache / Flu / Essential Thrombocythemia / bronchitis / dysfunction / cerebrovascular accident / nausea / pericardial effusion / heart disease / thrombocytopenia / Rhinitis / alopecia / cardiomegaly / pulmonary fibrosis / syncope / fatigue / angina pectoris / lymphadenopathy / gastritis / tachycardia / diarrhea / thrombocythemia secondary / sinusitis / muscle cramps / Constipation / Pruritus / back pain / cramps / pericarditis / Myelofibrosis / asthma / Arrhythmia / abdominal pain / insomnia / epistaxis / congestive heart failure / pneumonia / pulmonary infiltrates / hypertension / cardiomyopathy / Nutritional Disorders / thrombocythemia / disease / Arthralgia / heart block / Dyspnea / aphthous stomatitis / amnesia / chills / hematuria / Carcinogenesis / myeloproliferative disorders / migraine / cardiovascular disease / pulmonary hypertension / fever / seizure / Skin disease / melena / vomiting / Amblyopia / renal insufficiency / Myeloid Metaplasia / myocardial infarction / pleural effusion / heart failure / urticaria / diseases / pancreatitis / postural hypotension / Chronic Myelogenous Leukemia / atrial fibrillation / infection / deficiency / dizziness / Cough / renal failure / thrombosis / Depression / diplopia / Rash / Pharyngitis / Paresthesia / anemia / tinnitus / Dehydration / / MedicalTreatment contraception / / Organization US Federal Reserve / / Person Malaise Pain Pain (Abd) / / Position forward / / Product acetaminophen / hydroxyurea / anagrelide hydrochloride / ranitidine / allopurinol / amrinone / theophylline / sucralfate / digoxin / AGRYLIN / cilostazol / S-010 Page / Dimethyl Sulfoxide / Rx / furosemide / S-010 / / ProvinceOrState Newfoundland / New York / Pennsylvania / / Technology pharmacokinetics / /
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NDA[removed]S-010 Page 3 AGRYLIN® (anagrelide hydrochloride) Capsules Rx only