A conserved protonation-dependent switch controls drug binding in the Abl kinase Yibing Shana, Markus A. Seeligerb, Michael P. Eastwooda, Filipp Frankb, Huafeng Xua, Morten Ø. Jensena, Ron O. Drora, John Kuriyanb,1, and

First Page		Document Content
Date: 2010-09-27 16:06:44 Protein kinases Chemistry Piperazines Pyrimidines Organic chemistry Clinical medicine Protein kinase A Signal transduction Imatinib Protein kinase Tyrosine kinase ABL		A conserved protonation-dependent switch controls drug binding in the Abl kinase Yibing Shana, Markus A. Seeligerb, Michael P. Eastwooda, Filipp Frankb, Huafeng Xua, Morten Ø. Jensena, Ron O. Drora, John Kuriyanb,1, and Add to Reading List Source URL: www.deshawresearch.com Download Document from Source Website File Size: 628,04 KB Share Document on Facebook

	Targeting Vascular Endothelial Growth Factor Receptor 2 and Protein Kinase D1 Related Pathways by a Multiple Kinase Inhibitor in Angiogenesis and Inflammation Related Processes In Vitro DocID: 1v2t4 - View Document
	Journal of Cellular Biochemistry 103:972–Raf Kinase Inhibitor Protein Positively Regulates Cell–Substratum Adhesion While Negatively Regulating Cell–Cell Adhesion Kevin T. Mc Henry,1 Roberto Montesano,2 DocID: 1uOLU - View Document
	A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1 DocID: 1uLFX - View Document
	The mouse kinome: Discovery and comparative genomics of all mouse protein kinases Sean Caenepeel†, Glen Charydczak, Sucha Sudarsanam, Tony Hunter‡, and Gerard Manning§¶ *SUGEN, Incorporated, 230 East Grand Aven DocID: 1uFIN - View Document
	Die Protein KInase IKK epsilon ist ein potentielles Ziel für die Behandlung von entzündungsbedignter Hyperalgresie IκB-Kinase epsilon (IKKε) ist ein erst kürzlich identifiziertes Enzym, welches eine hohe Sequenzhomo DocID: 1uhU5 - View Document