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Biomolecules / Posttranslational modification / Neurological disorders / Aldehydes / Ketones / Methylglyoxal / Advanced glycation end-product / 3-Deoxyglucosone / Neurotoxicity / Chemistry / Biology / Biochemistry


Role of Methylglyoxal in Alzheimer’s Disease
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City

New York / Cleveland / Article / SH / /

Company

B. A. Callingham A. E. / MG BioMed Research International / R. A. Gomes A. E. / P. J. Thornalley S. P. / Creative Commons / Humana Press / Hindawi Publishing Corporation / /

Country

Italy / United States / /

Currency

pence / /

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Event

Product Issues / /

Facility

C. J. Pike / University of Bologna / /

IndustryTerm

glycation end-products / by-product / cellular systems / glycation end-product / phosphate / chemical nature / amino / Chemical and immunochemical characterization / metal ions / prokaryotic and mammalian systems / lipoxidation end products / food / high energy demand / hotspot site / aldehydic products / glycation end products / chemical process / intermediate products / physiological systems / lipid peroxidation systems / degradation product / food cooking / electronic energy / gas phase / /

MedicalCondition

Age-Related Disorders / chronic renal failure / Introduction Alzheimer’s disease / cerebrovascular disease / amyotrophic lateral sclerosis / Neuro-2A neuroblastoma cell line apoptosis / diabetic ketoacidosis / age-related diseases / neuronal dysfunction / tumor / mitochondrial dysfunction / Alzheimer’s disease / hypertension / cancer / disease / diabetic complications / ROS-mediated methylglyoxal injury / cognitive impairment / diabetes / neuroblastoma cells / common and lethal neurodegenerative disorder / cellular dysfunction / cognitive dysfunction / ketosis / vascular dementia / diabetes mellitus / Alzheimer disease / neurodegenerative diseases / inflammation / inflammatory responses / human disease / /

MedicalTreatment

chemotherapy / bypass / /

Organization

Italy Department of Pharmacy and Biotechnology / University of Bologna / Department for Life Quality Studies / National Academy of Sciences / New York Academy of Sciences / /

Person

D. Alexander Fried / Alma Mater Studiorum / Cristina Angeloni / Silvana Hrelia / K. M. Bieme / F. Dutra / V / M. O. Lederer / Monte di Bologna / /

Position

General / neurotoxic mediator / Academic Editor / /

Product

acetylcysteine / LG PC12 Radio / H3 / glycine / glucose metabolism / antioxidant / synapse / detoxifying ability / /

ProvinceOrState

New York / /

PublishedMedium

Current Opinion / Journal of Agricultural and Food Chemistry / Journal of Molecular Biology / Journal of Bacteriology / Journal of Food Science / The American Journal / Proceedings of the National Academy of Sciences / PLoS ONE / Microbiology / Biochemical Society Transactions / The Biochemical Journal / Annals of Internal Medicine / Journal of Neuroscience / /

Technology

alpha / Genomics / Neuroscience / Drug Metabolism / antibodies / Biotechnology / Transplantation / apoptosis / gene expression / chemotherapy / Bioelectronics / Dialysis / /

URL

http /

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