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Company Merck Sharp & Dohme Corp. / Merck & Co. Inc. / / Event FDA Phase / / Facility Laboratory Test Chemistry Hyperglycemia / Laboratory Abnormalities Increased / / IndustryTerm yellow solution / therapies for advanced or metastatic disease / treatment of patients with unresectable or metastatic melanoma / infusion solution / radiographic imaging / Monitor for signs and symptoms / / MedicalCondition Adverse Reaction General Disorders / Connective Tissue Disorders Arthralgia / partial seizures / suspected pneumonitis / greater hepatitis / TB / Immune-Mediated Pneumonitis Pneumonitis / Immune-Mediated Hyperthyroidism / HIV / greater nephritis / autoimmune nephritis / greater pneumonitis / syngeneic mouse tumor / Immune-Mediated Colitis Colitis / arthritis / Lymphatic System Disorders Anemia / cellulitis / M1c disease / nausea / nephritis / Laboratory Test Chemistry Hyperglycemia / Administration Site Conditions Fatigue / hepatitis B / hyperthyroidism / metastatic disease / colitis / melanoma / Hyponatremia / fatigue / Immune-mediated pneumonitis / Hematology Anemia / Stage M1c disease / interstitial nephritis / Immune-Mediated Nephritis / diarrhea / Immune-Mediated Hepatitis / hepatitis / Vitiligo / Immune-Mediated Hepatitis Hepatitis / constipation / Hypothyroidism Hyperthyroidism / pruritus / pneumonitis / Infections / Back pain / Hypoalbuminemia / Aminotransferase Hypocalcemia / greater hyperthyroidism / respiratory tract infection / sepsis / adrenal insufficiency / greater colitis / tumor / Abdominal pain / pneumonia / hemolytic anemia / Gastrointestinal Disorders Nausea / tumors / disease / brain metastases / liver metastasis / arthralgia / Hypothyroidism / dyspnea / Chills / Thoracic And Mediastinal Disorders Cough / Hypertriglyceridemia / decreased tumor / Carcinogenesis / Immune-Mediated Colitis / hyperglycemia / optic neuritis / Acute interstitial nephritis / inflammatory foci / exfoliative dermatitis / rhabdomyolysis / microscopic colitis / pain / Vomiting / Thyroid disorders / Immune-Mediated Nephritis Nephritis / myositis / pancreatitis / Psychiatric Disorders Insomnia / myasthenic syndrome / Isolated hypothyroidism / infection / Nervous System Disorders Headache / Dizziness / Skin And Subcutaneous Tissue Disorders Pruritus / autoimmune hepatitis / cough / Renal Failure / rash / chronic hepatitis B / inflammatory responses / anemia / interstitial lung disease / lymphocytic choriomeningitis virus / disorders / metastatic melanoma / Immunogenicity DRUG INTERACTIONS USE IN SPECIFIC POPULATIONS Immune-mediated colitis / uveitis / / MedicalTreatment intravenous infusion / thyroid hormone replacement therapy / contraception / / Organization DOSAGE AND ADMINISTRATION / FDA / INDICATIONS AND USAGE DOSAGE AND ADMINISTRATION / / / Position Adverse Reaction General / / Product DOSAGE FORMS AND STRENGTHS For injection / Sodium Chloride / Sterile Water / prednisone / for / / Technology antibodies / Pharmacokinetics / / URL www.fda.gov/medwatch / / SocialTag 
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use KEYTRUDA safely and effectively. See full prescribing information for KEYTRUDA. KEYTRUDA® (pembrolizumab) for injec