| Document Date: 2015-03-05 19:44:49
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City IFN / Burnaby / / Company Ian MacLachlan Tekmira Pharmaceuticals Corp. / RACE / GenBank / Avanti Polar Lipids Inc. / Sigma-Aldrich / Tekmira Pharmaceuticals Corp. / Cox / Integrated DNA Technologies / / Country Canada / / Currency pence / / Facility AS terminus / / IndustryTerm mRNA cleavage products / start site / disease site / cleavage products / cancer therapeutics / machinery / mRNA cleavage product / hPLK1 mRNA product / cleavage product / ligation site / chemical modification / chemical modification strategies / passive disease-site / in vivo applications / as cancer therapeutics / oncology applications / siRNA design algorithm / chemical modifications / / MedicalCondition total tumor / hepatic hep3B tumors / hepatocellular carcinoma cell lines / siRNA-based cancer / significant bone marrow dysfunction / viral infection / such tumor / established tumors / hepatic Hep3B tumor / control tumors / collected tumors / human tumor / Hep3B liver tumor / validated cancer / LS174T colon carcinoma / solid tumors / Neuro2a tumors / extensive macroscopic tumor / Hepatic Neuro2a tumor / H&E tumor / affected tumor / mitotic dysfunction / liver tumors / mouse cancer / inflammatory cytokines / choroidal neovascularization / orthotopic tumor / primary intrahepatic tumors / s.c. tumors / metabolic disorders / visible tumors / both hepatic and subcutaneous tumor / H&E-stained tumor / tumor / hepatic tumor / hepatic Neuro2a tumors / isolated tumor RNA / orthotopic liver tumor / cancer / tumors / hepatic Neuro2a tumor model / disease / resected hepatic Neuro2a tumors / hepatic tumors / human cancer / Hep3B tumor / s.c. Hep3B tumor / total Neuro2a tumor / direct tumor / extensive tumor / diseases / human HT29 colon cancer / RNAi-mediated tumor / Hep3B liver tumors / SCID / syngeneic Neuro2a tumor / human hepatocellular carcinoma / syngeneic Neuro2a liver tumors / established intrahepatic Hep3B tumors / inflammation / abundant tumor / / MedicalTreatment cancer therapeutics / / Organization i.v. administration / Repeat administration / siRNA administration / SNALP administration / / Person Lina Hu / Ellen Ambegia / Anna Fronda / Marjorie Robbins / Kevin McClintock / Adam D. Judge / / Position Images representative / representative / Judge / / Product PLK1424-2 / PCR / adenosine / / ProvinceOrState British Columbia / / PublishedMedium The Journal of Clinical Investigation / / Technology drug-delivery / CDMA / antibodies / siRNA / siRNA design algorithm / apoptosis / ATG / gene expression / DNA sequencing / http / pharmacodynamics / / URL http /
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