Serpell LC / Cold Spring Harbor Lab Press / Chance Laboratories / ABC / SDS solubility AB / Alzheimer’s Disease Core Center Pilot AG / DAPH SA / DAPH (20 "M) SA / Ligand / DAPHs SA / DuPont / Hess / M SA / /
Currency
USD / / /
Event
FDA Phase / Reorganization / /
Facility
Howard Hughes Medical Institute / Cambridge Center / Scale bar / †Whitehead Institute / Cold Spring Harbor / Massachusetts Institute of Technology / University of Pennsylvania School / The Scripps Research Institute / /
IndustryTerm
Chemical space / Prevention of transthyretin amyloid disease / reagents/analytic tools / reaction products / fluorescence tools / treatment of Alzheimer’s disease / /
MusicGroup
Alliance / M.I. / National / J.K. / /
Organization
University of Pennsylvania School of Medicine / Cambridge Center / University of Pennsylvania Alzheimer’s Disease Core Center / Fiber Assembly / Huntington’s Disease Society of America Postdoctoral Fellowship / Alzheimer’s Association / Massachusetts Institute of Technology / National Academy of Sciences / Department of Molecular Biology / Johanna Immerwahr Fund for Alzheimer Research Grant / Department of Biochemistry and Biophysics / Scripps Research Institute / American Heart Association / Howard Hughes Medical Institute / MIT Alliance / †Whitehead Institute for Biomedical Research / /
Person
Barbara J. Blanchard / Jonathan King / Vernon M. Ingram / R. Wickner / Martin L. Duennwald / P. Lansbury / Jr. / Alexa Fluor / Stephen L. Buchwald / James Shorter / Susan Lindquist / Edward J. Hennessy / Julie Su / Leslie M. Rozeboom / Huan Wang / Blake E. Roberts / Ashok A. Deniz / J. Weissman / Andrew D. Steele / G. Raymond / C. Glabe / Peter Weigele / /
Position
Investigator / scientist / Head / Author / scientist development grant / Tessier PM / /
Product
DAPH-1 / DAPH-6 / /
ProvinceOrState
Alberta / New Mexico / Pennsylvania / California / Massachusetts / /
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs Huan Wang*, Martin L. Duennwald†, Blake E. Roberts*, Leslie M. Rozeboom‡, Yingxin L. Zhang‡, Andrew D. Steele