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Proteins / E2F / Retinoblastoma protein / P16 / Cyclin / Restriction point / Neuroblastoma / P21 / Melanoma / Biology / Cell biology / Cell cycle


Microsoft PowerPoint - LEE011 presentation to pediatric ODAC_ Nov 5
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Company

Astex Cyclin / /

Continent

North America / /

Country

United States / /

Event

FDA Phase / /

MedicalCondition

ER+ breast cancer / Mandatory archival tumor / Highly aggressive cancer / tumor / melanoma / Heterogeneous tumor / liposarcoma / pRb+ tumors Dose escalation N / cancer / disease / extra-CNS tumor / Neuroblastoma High-risk Neuroblastoma / Third most common childhood cancer / highly malignant tumors / Dose expansion Tumor / solid tumors / neutropenia / high risk disease / cholestasis / BRAF/NRAS wild type melanoma / Neuroblastoma / lymphomas / rare tumors / /

MusicGroup

Nausea / /

Product

LEE011 / NB / Adults / /

ProvinceOrState

South Dakota / New Brunswick / /

Technology

Pharmacokinetics / /

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