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Intermediate filament / Keratin 14 / Keratin / Green fluorescent protein / Epidermolysis bullosa / Plectin / Vimentin / Actin / Phalloidin / Biology / Cytoskeleton / Keratins


The Mechanical Behavior of Mutant K14-R125P Keratin Bundles and Networks in NEB-1 Keratinocytes Daniel R. Beriault1, Oualid Haddad1, John V. McCuaig1, Zachary J. Robinson1, David Russell2, E. Birgitte Lane2,3, Douglas S.
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Document Date: 2014-08-23 10:22:37


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File Size: 1,21 MB

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City

Dundee / Guelph / Bradford / Bethesda / San Jose / Santa Cruz / /

Company

IgG / Adobe / Adobe Systems / Russell / Nikon Instruments Inc. / Creative Commons / Shimizu / Cytoskeleton Inc. / /

Country

United States / Canada / United Kingdom / Singapore / Scotland / /

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Event

Product Issues / FDA Phase / /

Facility

University of Dundee / Dalhousie University / College of Life Sciences / Scale bar / Institute of Medical Biology / University of Guelph / /

IndustryTerm

adjustment tools / acute cell straining protocols / mutant networks / paraformaldehyde solution / rubber substrate / rubber strip / cytokeratin networks / microtubule networks / keratin network / intermediate filament network / cytoskeletal networks / filamentous biopolymer networks / coated silicone rubber membranes / osmotic shock protocol / uniaxial cell-stretching device / cell stretching device / keratin networks / imaging / sparse network / filament networks / abnormal keratin-filament network / keratin filament network / mutant keratin network / labeled microtubule network / fragile networks / keratin filament networks / filament network / sparser keratin network / reagents/materials/analysis tools / microtubule network / intact keratin networks / /

MedicalCondition

muscular dystrophy / JE / fluid-filled blisters / hereditary skin blistering / strain / hypo-osmotic shock / Osmotic shock / epidermolysis bullosa / Plectin deficiency / Epidermolysis bullosa herpetiformis Dowling-Meara / stretch-induced necrosis / late-onset muscular dystrophy / necrosis / genetic disease / Epidermolysis bullosa simplex / greater strain-induced necrosis / inherited skin-blistering disease / inherited epidermolysis bullosa / significantly lower necrosis / EBS-like diseases / nocodazole-treated cultures exhibiting necrosis / inherited skinblistering disease / cellular necrosis / /

Organization

National Institute of Health / DAPI / University of Guelph / Abnormal / College of Life Sciences / Institute of Medical Biology / FDA / Department of Integrative Biology / University of Dundee / Dalhousie University / /

Person

Sukhminder Sawhney / Alexa Fluor / Wrote / Steve Wilson / John V / Arch Dermatol Res / Kyle Gillespie / Douglas Fudge / Santo Cruz / /

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Position

Greenberg HB / original author / Editor / Author / Porter / /

Product

hydrocortisone / filaments / EBS / response / /

ProvinceOrState

California / /

PublishedMedium

PLoS ONE / /

RadioStation

Davies AM / /

Technology

osmotic shock protocol / antibodies / electroporation / AVI / acute cell straining protocols / genotype / carried out using electroporation / /

URL

www.plosone.org / /

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