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Cell signaling / KIAA1524 / Apoptosis / AKT / Protein phosphatase 2 / Hepatocellular carcinoma / Targeted therapy / Erlotinib / Epidermal growth factor receptor / Biology / Chemistry / Medicine


Erlotinib derivative inhibits hepatocellular carcinoma by targeting CIP2A to reactivate protein phosphatase 2A
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Document Date: 2014-07-31 08:37:39


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File Size: 2,33 MB

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Glostrup / Ann Arbor / Osaka / Taipei / Pittsburgh / Changhua / Indianapolis / St. Louis / Rockville / Helsinki / Baltimore / Cambridge / San Diego / Chicago / Chiayi / Edinburgh / /

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SPSS Inc. / Packman LC / Sherman M. Management / Sk-Hep1 PLC / BD Biosciences / IgG / LG / Health Science Research Resources Bank / Bayer Pharmaceuticals / Bruix J / Roche Pharmaceuticals / HP / Creative Commons / Macmillan Publishers Limited / /

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Switzerland / Japan / United Kingdom / Scotland / Denmark / Taiwan / United States / /

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National Taiwan University / Jen Catholic University / DNA complex / Cardinal Tien Hospital / National Laboratory Animal Center / St. Martin De Porres Hospital / Fu Jen Catholic University / Institute of Biopharmaceutical Sciences / National Taiwan University Hospital / National Yang-Ming University / Kaohsiung Medical University / Trail PA / Changhua Christian Hospital / Taipei Veterans’ General Hospital / /

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IndustryTerm

genetic regulatory networks / cancer therapy / /

MedicalCondition

unresectable hepatocellular carcinoma / cervical and endometrial cancers / JE / potential cancer / advanced hepatocellular cancer / hepatitis B / chronic inflammation / endometrial carcinoma / prostate cancer / PLC5 xenograft tumor / breast cancer / lung and oral cancer / human triple negative breast cancer / leukemia / tumor / cervical and endometrial carcinoma / cancer / TD52-induced HCC tumor / tumors / hepatocellular carcinoma / Hino O. Hepatitis C / TD52-induced cancer / HCV / C infection / malignant diseases / mean tumor / human hepatocellular carcinoma / clinical tumor / S-phase arrest cancer / tissue and human colon carcinoma / advanced disease / Wilms’ tumors / advanced hepatocellular carcinoma / vivo tumor / clinical liver tumor / reluctant tumor / Hepatocellular cancer / hepatitis C / J Cancer / Xenograft tumor / important tumor / Piche A. Ovarian cancer / human renal cell carcinoma / PLC5 xenograft tumors / human breast cancer / cancers / necrosis / common cancer / Disease / modest disease / Decreased tumor / TD52-induced tumor / Pisani P. Estimating the world cancer / human colorectal carcinoma / different malignant diseases / lung cancer / Mol Cancer / /

MedicalTreatment

radiotherapy / Surgery / cancer therapy / anticancer therapy / chemotherapy / /

OperatingSystem

Microsoft Windows / /

Organization

Taipei Veterans’ General Hospital / St. Martin De Porres Hospital / Kaohsiung Medical University / Kaohsiung / National Taiwan University / School of Medicine / Department of Medicine / Fu-Jen Catholic University / FDA / Institutional Laboratory Animal Care and Use Committee / National Yang-Ming University / Institute of Biopharmaceutical Sciences / National Laboratory Animal Center / Cardinal Tien Hospital / National Science Council / National Taiwan University Hospital / Use Committee / Changhua Christian Hospital / Department of Medical Research / 2National Center of Excellence for Clinical Trial and Research / 9Medical Research Center / /

Person

Wang H. Multiple / /

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Position

Luciferase reporter / pathologist / Vitek MP / representative / Cao / El-Serag HB / reporter / Marshall / /

Product

Nexavar / Tarceva / sodium chloride / dimethyl sulfoxide / /

ProvinceOrState

Maryland / South Dakota / New Hampshire / /

PublishedMedium

PloS One / /

Region

Asia-Pacific / /

Technology

siRNA / apoptosis / DNA Chip / chemotherapy / treating cancer / alpha / Genomics / electrophoresis / antibodies / Biotechnology / Cell Signaling / transplantation / drug development / /

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