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RNA splicing / Gene expression / RNA / Molecular biology / Alternative splicing / Exon / SnRNP / Precursor mRNA / Intron / Biology / Genetics / Spliceosome


Theory on the Coupled Stochastic Dynamics of Transcription and Splice-Site Recognition Rajamanickam Murugan1,2, Gabriel Kreiman2,3,4* 1 Department of Biotechnology, Indian Institute of Technology Madras, Chennai, India,
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Document Date: 2012-11-02 13:16:48


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File Size: 1,79 MB

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Chennai / Boston / Cambridge / Affymetrix Transcript / /

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Affymetrix / Creative Commons / /

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United States / India / /

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II complex / Indian Institute of Technology Madras / RNAPII complex / Children’s Hospital / Harvard University / /

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minimum search time / snRNP search processes / pattern prediction algorithms / search times / search process / snRNP search process / ultimate mature mRNA product / minimum achievable search time / explicit real solution / computational algorithms / minimum achievable overall search time / chemical reaction scheme / 1D+3D search time / stochastic search dynamics / snRNP search mode / 1D3D search mode / particular solution / snRNP search / donor site / average overall search time / search time scales / search dynamics / splice pattern prediction algorithms / overall search / donor splicing site / overall search time / 3D search / 3D search mechanisms / biweight algorithm / pure 3D search / post-transcriptional processing / ultimate product / transcriptional machinery / search time / search mechanism / /

Organization

Harvard Medical School / Swartz Center for Theoretical Neuroscience / National Institute of Health / Harvard University / National Science Foundation / Center for Genomic Regulation / Children’s Hospital Boston / Department of Biotechnology / Indian Institute of Technology Madras / /

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original author / Editor / RT / mature messenger / random walker / Author / /

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Eastman Kodak ZxD Camcorder / /

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Massachusetts / /

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PLOS Computational Biology / the PLOS Computational Biology / /

Technology

Neuroscience / Tukey biweight algorithm / Biotechnology / hybridization / DNA binding / human genome / splicing pattern prediction algorithms / DNA Chip / splice pattern prediction algorithms / /

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www.ploscompbiol.org / /

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