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Published OnlineFirst September 22, 2009; DOI:[removed].CCR[removed]Synergistic Effects of Oncolytic Reovirus and Cisplatin Chemotherapy in Murine Malignant Melanoma Hardev S. Pandha, Lucy Heinemann, Guy R. Simp
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Document Date: 2013-12-23 12:38:23


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City

Forsyth / Guildford / Surrey / Leeds / Calgary / London / /

Company

Merck Biosciences Ltd. / Agilent Technologies UK Ltd. / Ben Venue Laboratories Inc. / Abbas AE / GraphPad Software Inc. / Oncolytics Biotech Inc. / Qiagen Inc. / B&K Universal Ltd. / Bio-Rad / Ely Lilly and Co. / 3Oncolytics Biotech Inc. / Cambrex Bio Science Rockland Inc. / Bristol-Myers Squibb Co. / Beckman Coulter / Cox / Mayne Pharma Plc / Chester Beatty Laboratories / Oncolytic Biotech Inc. / /

Country

Canada / United Kingdom / /

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Event

FDA Phase / /

Facility

James's University Hospital / Royal Surrey County Hospital pharmacy / University of Surrey / /

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IndustryTerm

treatment of ovarian cancer / Cancer Therapy / cancer therapies / human tumor cells cytokine network / tumor site / treatment of melanoma / treatment of pancreatic cancer / therapy of metastatic cancer / cancer treatment / sonic hedgehog signaling network / virus solution / /

MedicalCondition

inflammatory response / mouse melanoma / ovarian cancer / JE / human tumor / B16.F10 mouse melanoma / human melanoma / melanoma / colorectal liver metastases / Reduced tumor / Rous sarcoma / Brain tumor / human non-small cell lung cancer / colon carcinoma / tumor / Replicative oncolytic herpes simplex viruses / cancer / tumors / subcutaneous tumors / particularly aggressive cancer / patients' disease / malignant melanoma / murine melanoma / oncolytic herpes simplex virus / reovirusresistant tumor / local inflammatory responses / earlypassage melanoma / increased tumor / infection / s.c. B16.F10 tumors / herpes simplex virus / inflammatory / B16.F10 tumors / metastatic melanoma / productive infection / significantly delayed tumor / Boucher Y. Cancer / metastasis / murine tumors / reovirus infection / novel cancer / herpes / advanced melanoma / J Cancer / human and murine melanoma / murine lymphoma / ribonucleotide reductase-negative herpes simplex virus / Tumor infection / attractive cancer / reoviral infection / malignant pleural mesothelioma / inflammatory cytokines / combination cancer / head and neck cancer / pancreatic cancer / squamous cell carcinoma / Murine Malignant Melanoma Hardev S. Pandha / disease / immunocompetent tumor / inflammatory cytokine response / advanced cancer / local inflammatory cell kill / pancreatic carcinoma / reovirus-treated tumor / metastatic malignant melanoma / metastatic cancer / another mouse melanoma / recurrent malignant gliomas / thereby less tumor / diffuse liver metastases / inflammatory cytokine gene up-regulation / /

MedicalTreatment

radiotherapy / radiation / Cancer Therapy / Immunosuppression / cancer therapies / oncolytic virus therapy / cisplatin chemotherapy / CCR / chemotherapy / gene therapy / viral therapy / /

Organization

St. James's University Hospital / American Association for Cancer Research Published OnlineFirst / Institute for Cancer Research / University of Surrey / 2Cancer Research UK Clinical Centre / American Association for Cancer Research / Royal Surrey County Hospital / Postgraduate Medical School / AACR Publications Department / /

Person

Christine White / Kim Morton / Arch Virol / Guy R. Simpson / Van Meir / Lucy Heinemann / L HBSS / Katie Twigger / /

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Position

recurrent head / representative / /

Product

carboplatin / Cisplatin / cyclosporine / mitomycin / paclitaxel / EXPO32 ADC / IL-10 / penicillin / cyclophosphamide / fluorouracil / dacarbazine / GeneSpring / single / /

ProvinceOrState

South Carolina / Alberta / Delaware / /

PublishedMedium

Cancer Research / /

RadioStation

Heart 6 / /

Technology

radiation / microarray system / apoptosis / DNA Chip / gene expression / Chemotherapy / treating cancer / ADC / antibodies / Hybridization / cell signaling / gene therapy / completed using the Agilent microarray system / /

URL

http /

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