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© The American Society of Gene Therapy original article A Phase I Trial of Intratumoral Administration of Reovirus in Patients With Histologically Confirmed
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Document Date: 2013-12-23 11:30:37

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City

Wilcox / Forsyth / Philadelphia / Newcastle / Rabkin / Helsinki / Birmingham / Rewcastle / Schiff / Calgary / /

Company

Qiagen / Wilson / Oncolytics Biotech / the AEs / Tyler / 8Oncolytics Biotech Inc. / /

Country

Canada / United States / /

Currency

AOA / /

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Event

FDA Phase / /

Facility

University of Alabama / Hospital Drive NW / Tom Baker Cancer Centre / Southern Alberta Cancer Research Institute / University of Calgary / National Cancer Institute of Canada Clinical Trials Group / /

IndustryTerm

magnetic resonance imaging / therapeutics for cancer / therapy of metastatic cancer / clinical applications / multiplanar magnetic resonance imaging / Post-treatment magnetic resonance imaging / magnetic resonance imaging evaluation / /

MedicalCondition

Anaplastic astrocytoma / recurrent glioma / JE / viral infection / reovirus-induced myocarditis / high-grade glioma / Pulmonary / Patients With Histologically Confirmed Recurrent Malignant Gliomas Peter Forsyth1 / prostate cancer / breast cancer / meningismus / brain tumor / brain tumors / leptomeningeal metastases / tumor / human malignant glioma / clinical trials using herpes / Cancer / tumors / brain metastases / diffuse viral encephalitis / infectious virus / advanced solid tumors / chronic / cerebral edema / focal/generalized encephalitis / fever / kill tumor / vomiting / malignant glioma / human high-grade gliomas / encephalitis / tissue culture infectious dose / medulloblastoma / stable disease / vaccinia virus / herpes simplex virus / supratentorial malignant glioma / residual/ recurrent tumor / vesicular stomatitis virus / tumours / Recurrent/progressive disease / malignant tumor / lethal infection / headache / relapsed malignant glioma / nausea / replication-competent herpes simplex virus / experimental human malignant gliomas / herpes / colon cancer / Gliomas / focal seizure / recurrent glioblastoma multiforme / host tumor / gliosarcoma / pulmonary embolism / systemic cancer / infections / gliosarcoma component / anaplastic astrocytomas / necrosis / cutaneous metastases / severe combined immunodeficiency / disease / glioblastoma multiforme / progressive disease / tumour / Apnea / advanced cancer / metastatic cancer / spinal and leptomeningeal metastases / transient intratumoral inflammation / recurrent malignant gliomas / malignant gliomas / bilateral hygromas / recurrent seizures / tuberculosis / trials using measles virus / dehydration / /

MedicalTreatment

Molecular Therapy / radiotherapy / Surgery / radiation / radiosurgery / Adjuvant chemotherapy / chemotherapy / antiviral therapy / antibiotic prophylaxis / gene therapy / drug therapy / brain brachytherapy / /

MusicGroup

Nausea / /

Organization

World Health Organization / Data Safety Monitoring Board / Southern Alberta Cancer Research Institute / American Society of Gene Therapy MGs / Division of Neurosurgery / National Cancer Institute of Canada Clinical Trials Group / Thompson8 and Mark Hamilton2 / 3 / 9 Department of Oncology / American Society of Gene Therapy / Reovirus administration / University of Alabama at Birmingham / 3Clark Smith Integrated Brain Tumor Research Centre / Department of Pathology / Foothills Medical Centre / Tom Baker Cancer Centre / Intratumoral Administration of Reovirus / University of Calgary / Division of Neuropathology / /

Person

Cheryl Ann / Maureen Vallee / Brasher / Howley / /

Position

Prime Minister / neurosurgeon / private investigator / CEO / Hunter / /

Product

chorionic gonadotropin / HSV1716 injection / ganciclovir / Viral Injection / G207 / viral / dose / /

ProvinceOrState

New Brunswick / Alabama / Maine / Louisiana / Alberta / South Dakota / Pennsylvania / /

Region

Southern Alberta / /

Technology

radiation / X-ray / magnetic resonance imaging / chemotherapy / Neurosurgery / electrophoresis / tomography / antibodies / Gene Therapy / Diagnostic Imaging / /

URL

www.moleculartherapy.org / /

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