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Cell signaling / Intracellular receptors / Retinoid X receptor / Constitutive androstane receptor / Orphan receptor / Liver X receptor / Farnesoid X receptor / Pregnane X receptor / Cholesterol 7 alpha-hydroxylase / Biology / Transcription factors / Cell biology


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City

MOORE ET / Leitersdorf / Lochansky / Washington / /

Company

Sowers LC / Miller AB / Pirro AE / LXR / Ligand / Liverman AB / Cellular Biosciences / Kliewer SA / Cantorna MT / Chao LC Li / Jones SA / DeLuca HF / /

Country

Japan / /

Currency

pence / SHP / USD / /

/

Event

Product Issues / FDA Phase / /

Facility

Howard Hughes Medical Institute / Pike JW / C terminus / University of Pittsburgh / The University of Tokyo / University of Texas Southwestern Medical Center / Baylor College of Medicine / The Institute of Molecular / /

IndustryTerm

chemical space / natural product / protein products / treatment of osteoporosis / chemical tool / fulllength product / potential therapeutic applications / chemical defense response / potential applications / chemical stresses / adjacent site / Prevention of cholesterol gallstone disease / /

MedicalCondition

bone deformity / show alopecia / JE / hypocalcemia / extrahepatic cholestasis / muscle weakness / alopecia / liver tumors / hypocalcemic vitamin D-resistant rickets / chronic xenobiotic stress-induced liver tumorigenesis / disorder / psoriasis / rickets / Breast cancer / infertility / zoxazolamine-induced paralysis / paralysis / insulin resistance / hereditary diseases / cancer / secondary hyperparathyroidism / disease / atherosclerosis / atherogenesis / hyperglycemia / tetany / vitamin D-dependent rickets / hypocalcemic rickets / cholesterol gallstone disease / cardiovascular disease / hyperlipidemia / vitamin D deficiency / much more atherosclerosis / metabolic syndrome / high cholesterol / D- dependent hereditary rickets / ER-positive tumors / osteoporosis / deficiency / inflammation / diet-induced obesity / cholestasis / Human disease / Structural disorder / vitamin Ddependent rickets / /

NaturalFeature

Cantorna mountain / HF mountain / /

Organization

American Society for Pharmacology and Experimental Therapeutics Pharmacol / University of Texas Southwestern Medical Center / Dallas / Center for Pharmacogenetics / American Society for Pharmacology / Department of Pharmacology / Department of Molecular / Department of Molecular and Cellular Biology / Robert A. Welch Foundation / Baylor College of Medicine / Houston / Institute of Molecular / U.S.A International Union of Pharmacology / University of Pittsburgh / Pittsburgh / University of Tokyo / Tokyo / Howard Hughes Medical Institute / /

Person

DAVID J. MANGELSDORF / Van Herck / Van Etten / RUI XIAO / DANIEL R. SCHMIDT / SHIGEAKI KATO / Willson / Van Cromphaut / DAVID D. MOORE / wei zi / Shulman / Arch Biochem Biophys / Ann Med / STEVEN A. KLIEWER / /

Position

investigator / Bone Miner / D.J. / Brewer HB / receptor-binding protein/mediator / cao / Major / /

Product

acetaminophen / dexamethasone / clotrimazole / Vitamin D / rifampin / glycine / taxol / SR12813 / growth retardation / insulin secretory capacity / uterine hypoplasia / bile / bone formation / drug metabolism / /

ProvinceOrState

Texas / Alabama / Washington / Pennsylvania / /

PublishedMedium

Molecular and Cellular Biology / /

RadioStation

Anisfeld AM / Fivush AM / Pierce AM / Zavacki AM / /

Technology

genomics / drug metabolism / X-ray / cloning / DNA binding / Pharmacogenetics / artificial intelligence / gene expression / crystallization / /

URL

http /

SocialTag