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Apoptosis / BH3 interacting-domain death agonist / Fas receptor / Bcl-2 family / Caspase / Cisplatin / Bcl-2-associated X protein / Bcl-2 / Poly ADP ribose polymerase / Biology / Cell biology / Programmed cell death


Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer
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Document Date: 2012-12-20 05:58:57


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Leica Microsystems / Adelaide SA / Cell Signalling Technology Inc. / Sigma-Aldrich / Bemis / Mayne Pharma / Stephens / TARGET / Becton Dickinson / Creative Commons / Echelon Biosciences Inc. / Microsoft / Macmillan Publishers Limited / /

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Australia / United Kingdom / Germany / United States / /

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pence / /

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Product Issues / /

Facility

Hodgkin Building / Roswell Park Memorial Institute / University of Leicester / St James’ Hospital / University Belfast / /

IndustryTerm

death receptor apoptosis machinery / therapies for non-small cell lung cancer / model systems / /

MedicalCondition

cisplatin-resistant non-small-cell lung cancer I Paul1 / melanoma / non-small-cell lung cancer / non-small cell lung cancer / mitochondrial dysfunction / cancer / NSCLC / BRCA1-deficient non-small cell lung cancer / Cancer Lung cancer / non-smallcell lung cancer / nonsmall cell lung cancer / HT29 human colon cancer / primary resected non-small-cell lung cancer / tumours / advanced disease / DF / human colon cancer / colorectal cancer / nonsmall cell lung carcinoma / carcinoma / J Cancer / mutant EGFR-dependent lung adenocarcinomas / MS / advanced non-small-cell lung cancer / lung cancers / squamous cell carcinoma / Disease / human lung cancer / Platinum resistant cancer / tumour / resected nonsmall-cell lung cancers / Lung Cancer / lung adenocarcinomas / anaplastic lymphoma kinase / /

MedicalTreatment

bypass / chemotherapy / adjuvant therapy / /

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Excel / conducted using Microsoft Office Excel / /

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Burgess Hill / /

Organization

University of Leicester / Northern Ireland HSC R&D Office / British Lung Foundation / Centre for Cancer Research / Roswell Park Memorial Institute / Department for Education and Learning / St James’ Hospital / /

Person

Fellowship / Alexis Biochemicals / Frederick / Cell Biology / /

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Position

BCL2-interacting mediator / Representative / Ireland *Corresponding author / Queen / Hunter / Clinician Scientist / /

Product

cisplatin / Sigma / penicillin / ASM / apoptosis / mitochondrial signalling / /

ProvinceOrState

Sussex / South Dakota / /

PublishedMedium

Cancer Research / /

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Groeger AM / /

Region

Northern Ireland / /

Technology

siRNA / apoptosis / chemotherapy / alpha / antibodies / Biotechnology / silenced using siRNA / /

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http /

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