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Health / Aging-associated diseases / Genetics / Lung cancer / Genetic epidemiology / Genome-wide association study / Chronic obstructive pulmonary disease / Single-nucleotide polymorphism / Non-small-cell lung carcinoma / Medicine / Biology / Smoking


Lung Cancer Susceptibility Model Based on Age, Family History and Genetic Variants Robert P. Young1*, Raewyn J. Hopkins1, Bryan A. Hay1, Michael J. Epton3, Graham D. Mills4, Peter N. Black1, Heather D. Gardner1, Richard
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City

Canterbury / Auckland / Wellington / /

Company

Eaton / Ge / Holm NV / Medizintechnik AG / Creative Commons / Donnelly / Synergenz BioSciences / Schwartz AG / susceptibility AG / Samsung / /

Country

Switzerland / Sweden / New Zealand / Finland / Denmark / /

Currency

CYP / pence / Rs / USD / /

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Facility

University of Otago / Auckland Hospital / Stanford University / Australian Genome Research Facility / University of Auckland / Mayo clinic / Waikato Hospital / /

IndustryTerm

recruitment protocol / risk based tools / risk tools / risk tool / risk assessment tools / /

MedicalCondition

both lung cancer / pleural effusions / DF / obstructive pulmonary disease / COPD / alpha1-antitrypsin deficiency / optimized lung cancer / chronic smokers / airway inflammation / undiagnosed prostate cancer / nonsmall cell cancer / chronic inflammation / lung disease / Xeroderma Pigmentosum / Pulmonary inflammation / non-small cell lung cancer / Risk Model inflammatory cytokines / inflammatory stimulus / esophageal cancer / either COPD / Parameter Lung Cancer N / squamous cell cancer / prostate cancer / MS / chronic bronchitis / lung cancers / total lung cancer / asthma / co-existing COPD / cancers / cancer / each lung cancer / primary lung cancer / Human lung cancer / lung carcinogenesis / Spirometric COPD / emphysema / Carcinogenesis / chronic obstructive pulmonary disease / Chronic / Tissue necrosis / both COPD / BRCA1-associated ovarian cancer / Lung Cancer / human non-small-cell lung cancer / radiographic emphysema / genetic factors underlying lung cancer / small cell cancer / airways inflammation / inflammation / combined lung cancer / /

MedicalTreatment

surgery / /

Organization

Waikato Hospital / Genome-wide association / Health Research Council of New Zealand / Auckland Hospital / Multi-Region Ethics Committee / Auckland Medical Research Foundation of New Zealand / American Thoracic Society / University of Otago / Department of Medicine / Stanford University / Department of Oncology / Cumulative association / Research Fund / University of Auckland / /

Person

Minor Minor / Robert Young / Ann Hum / Brit Med / /

Position

investigator / original author / Editor / model development In / risk model for lung cancer / Carpenter / Author / Major / multigene model for lung cancer / same investigator / representative / Scientific Advisor / /

Product

acetylcysteine / SNPs / nicotine / /

ProvinceOrState

Oregon / Delaware / /

PublishedMedium

PLOS Genetics / PLoS ONE / /

SportsLeague

Stanford University / /

Technology

genotyping / apoptosis / same recruitment protocol / Pharmacogenetics / aero / SNP / genotype / /

URL

www.plosone.org / www.mskcc.org / www.agrf.com.au / www.hapmap.org / www.sequenom.com / /

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