Protein Data Bank / Pearson / Elsevier Ltd / Garland Publishing Inc. / Jeanfavre D.D. / Intel / Icahn Laboratory / /
Country
United States / / /
Event
Patent Filing / Environmental Issue / /
Facility
Princeton University / LewisSigler Institute / Lewis-Sigler Institute / /
IndustryTerm
characterized single-domain allosteric systems / low-energy excitations / conserved networks / energy minimum / remote site / energy scale / Minimum energy compact structures / coupled site / low energy / immune and central nervous systems / free energy / hydrophobic energy function / structure prediction algorithm / low-energy conformations / energy change / multidisciplinary technologies / conformational energy / local-energy minimum / energy matrix / allosteric systems / dot product / octanol solution / low-energy burial modes / energy landscapes / lowest-energy burial modes / molecular dynamics-simulation algorithms / lowest-energy combination / applicable tool / low-energy structural rearrangement / low-energy modes / lowest energy / expected free-energy change / hydrophobic burial energy / energy / /
Organization
United States Patent and Trademark Office / Lewis-Sigler Institute for Integrative Genomics / LewisSigler Institute for Integrative Genomics / Princeton University / /
Person
Gomes / Nat / E. Shakhnovich / V / /
Position
author / representative / ACKNOWLEDGMENTS The author / /
Product
isoflurane / /
ProgrammingLanguage
MATLAB / /
ProvinceOrState
Nova Scotia / /
Technology
Genomics / LFA-1 using multidisciplinary technologies / molecular dynamics-simulation algorithms / structure prediction algorithm / 2 Duo Processor / drug design / simulation / /
Allostery in Protein Domains Reflects a Balance of Steric and Hydrophobic Effects