| Document Date: 2013-12-03 15:17:37
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Company PET / / Event FDA Phase / / IndustryTerm Pre-operative imaging / / MedicalCondition residual tumor / adult and pediatric gliomas / tumor / high-grade gliomas / residual disease / infectious units / tumors / disease / strain / TBI / glioblastoma multiforme / glioma / dysfunction / host disease / progressive disease / only partial tumor / Pediatric high grade gliomas / herpes / Hepatitis C / Hepatitis B / metastatic disease / recurrent high-grade gliomas / pulmonary / encephalitis / systemic viremia / anaplastic ganglioglioma / high grade astrocytoma / infection / gliosarcoma / anaplastic oligodendroglioma / illness / refractory high-grade gliomas / infections / glioblastoma / / MedicalTreatment antiretroviral therapy / contraceptive method / platelet transfusions / chemotherapy / radiotherapy / Bone Marrow Transplant / total body irradiation / surgery / immunotherapy / Radiation / viral therapy / antiviral therapy / adjuvant therapy / / Organization intratumoral/peritumoral administration / / Position Vp / neurosurgeon / / Product pseudo / dexamethasone / acyclovir / ganciclovir / HSV1716 injection / Neulasta / PBTC-037 / / Technology Radiation / ADC / level 1 NCI Protocol / antibodies / chemotherapy / spectroscopy / 3 NCI Protocol / MRI / 2 NCI Protocol / /
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NCI Protocol #: PBTC-037 Version Date: November 19, 2013 Abstract and Schema: Description and Rationale: Pediatric high grade gliomas have a progressive initial course and high risk of relapse/