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Cell signaling / Transcription factors / Progesterone receptor / Estrogen receptor / Estrogen-related receptor alpha / Tamoxifen / Steroid hormone receptor / Orphan receptor / Selective estrogen receptor modulator / Biology / Intracellular receptors / Cell biology


j1 1 Nuclear Receptors as Drug Targets: A Historical Perspective of Modern Drug Discovery Eckhard Ottow and Hilmar Weinmann
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Document Date: 2009-09-25 08:33:26

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File Size: 291,02 KB

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City

Weinheim / /

Company

WILEY-VCH Verlag GmbH & Co. KGaA / Merck / Ligand / /

IndustryTerm

chemical probes / chemical development / nonsteroidal chemical entities / treatment of prostate cancer / endocrine regulatory systems / development / treatment of breast cancer / greater therapeutic applications / treatment for menopausal symptoms / industrial research / today’s analytical tools / treatment for ER-positive breast cancer / treatment of cholestatic liver disease / chemical structure / bioinformatic query tools / therapeutic applications / /

MedicalCondition

stress-related diseases / mammary cancer / cancer / cholestatic liver disease / disease / rheumatoid arthritis / diabetes / allergy / estrogen-responsive breast cancers / endometrial cancer / osteoporosis / hay fever / prostate cancer / breast cancer / ER-positive breast cancer / disorders / asthma / /

MedicalTreatment

oral contraceptives / contraception / fertility control / /

Person

Gregory Pincus / Eckhard Ottow / /

Position

reporter / /

Product

levonorgestrel / estradiol / prednisolone / cortisone acetate / dexamethasone / Discovery 4 1.2.3 Progesterone Receptor Research Progesterone / testosterone / vitamin D / spironolactone / Ortho-Novum / Estrone / Enovid / /

Technology

Drug Discovery / antibodies / gene expression / drug design / cloning / human genome / /

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