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Coagulation system / Serpin / Biochemistry / Serine protease / Protease / Enzyme inhibitor / Factor X / Insulin-degrading enzyme / Discovery and development of HIV-protease inhibitors / Biology / Chemistry / Enzymes


A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies
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Document Date: 2012-07-14 18:36:39

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File Size: 1,39 MB

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City

San Francisco / Palo Alto / /

Company

Protein Data Bank / Genentech / USA 4 Genencor Inc. / A11 / scFv / Elsevier Ltd. / Schrödinger LLC / /

Country

United States / Singapore / /

Currency

pence / /

/

Facility

Fab library / Fab scaffold / Genentech Hall / University of California / /

IndustryTerm

active site / clinical applications / matriptase active-site / matriptase active site / heavy chain / enzyme machinery / side chain / energy / protease active site / matriptase binding energy / light chain / /

OperatingSystem

L3 / /

Organization

Department of Pharmaceutical Chemistry / University of California / San Francisco / /

Person

Melody S. Lee / Eric L. Schneider / Mick Ward / Aida Baharuddin / I. Wilson Keywords / Christopher J. Farady / Charles S. Craik / David H. Goetz / /

Position

*Corresponding author / Prime Minister / /

Product

Humira / polyethylene glycol / dimethyl sulfoxide / /

ProvinceOrState

Alabama / California / /

PublishedMedium

Journal of Molecular Biology / /

Technology

Antibodies / phage display / /

URL

www.sciencedirect.com / /

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