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City Philadelphia / Samyo / L. A. / Vienna / Rochester / Farnell / Madison / / Company Baue A. E. / Draper / Mosby-Year Book Inc / Tran D. D. / Norton / Russell / Kohler / / Country Vietnam / / Currency pence / / Event Product Issues / / Facility George Washington University / University of Wisconsin-Madison Medical School / American College of Chest Physicians/Society / Mayo Clinic / / IndustryTerm APACHE scoring systems / pharmacological tools / blood banking capabilities / menhaden oil / blood products / organ systems / / MedicalCondition inflammatory response / hyperdynamic septic shock / ICU syndrome / gram-negative septicemia / Ventricular tachycardia / initial disease / secondary pneumonitis / infectious process / hepatic and renal dysfunction / initial injury / coma / dysfunction / secondary infection / leukocytosis / Pulmonary / endotoxin hypotension / injury / septic shock / MODS intestinal dysfunction / diarrhea / nosocomial infections / syndrome's / cardiac arrest / illness / burn injury / renal dysfunction / pulmonary vasoconstriction / asthma / infectious nidus / entirely new disease / endotoxic shock / endotoxemia and endothelial dysfunction / gramnegative bacteremia / endothelial dysfunction / deep venous thrombosis / Systemic inflammatory response syndrome / fever / Chronic disease / severe adult respiratory distress syndrome / specific disease / ventricular fibrillation / endogenous systemic inflammatory response / infection / isolated organ injury / Acute renal failure / Serotonin Reactive oxygen species Lysosomal enzymes Fibronectin Tumor necrosis / intestinal dysfunction / acute respiratory failure / individual organ dysfunction / hemorrhagic shock / inflammatory process / gram-negative sepsis / acquired immunodeficiency syndrome / Additional organ dysfunction / microbiologic infection / D. A. Endotoxin shock / hepatic dysfunction / Encephalopathy / severe illness / pulmonary embolism / organ dysfunction / acalculous cholecystitis / sepsis / sleep deprivation / acute lung injury / hypovolemic and septic shock / arterial oxygen content nary artery disease / uncontrolled infection / immune dysfunction / systemic inflammatory response / acid-base imbalance / disease / relatively common syndrome / adult respiratory distress syndrome / shock / documented infection / ileus / T. Acute lung injury / tumor necrosis / myocardial infarction / ruptured aortic aneurysm / clinical sepsis / documented infections / pulmonary dysfunction / abdominal aortic aneurysm / abscess / myocardial dysfunction / syndrome / Organ Dysfunction Syndrome / / MedicalTreatment enteral feeding / Incision / nutritional support / enteral nutrition / surgery / immunotherapy / continuous positive airway pressure / immunosuppression / drainage / resuscitation / positive end expiratory pressure / antibiotics / cardiopulmonary resuscitation / mechanical ventilation / / NaturalFeature Murray / / Organization Mayo Foundation / Rochester / George Washington University / YALE / Society of Critical Care Medicine Consensus Conference / American College / University of Wisconsin / / Person Michael J. Murray / Lotring / Douglas B. Coursin / William Knaus / Ilstrup / Van Der Meulen / Gillespie / Murphy / Van Bebber / Van Schijndel / / Position D. J. / specific endogenous mediator / Fisher / / Product methylprednisolone / cyclosporine / Glucagon / gentamicin / epinephrine / A2 / haloperidol / naloxone / nystatin / oxygen delivery / oxygen consumption / / ProvinceOrState Minnesota / ARDS / S. K. / M. B. / Wisconsin / South Dakota / / PublishedMedium Critical Care Medicine / / Technology antibodies / / SocialTag 
YALE JOURNAL OF BIOLOGY AND MEDICINE[removed]), pp[removed]Copynight C[removed]All rights erscved. Multiple Organ Dysfunction Syndrome Michael J. Murray, M.D., Ph.D.a, and Douglas B. Coursin, M.D.b aDepartnent ofAnesthesi