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Malaria / Biology / Tropical diseases / Plasmodium falciparum / Sickle-cell disease / Antimalarial medication / Mosquito net / Immune system / Genetic resistance to malaria / Medicine / Health / Plasmodium


Open access, freely available online PLoS MEDICINE An Immune Basis for Malaria Protection by the Sickle Cell Trait
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City

Kilifi / Oxford / London / /

Company

Fleming / IgG / LG / Wellcome Trust / Proc Natl Acad Sci U S A / Lehman / Boyo AE / Creative Commons / StataCorp / Donnelly / Leverhulme Trust / /

Country

Sudan / Gambia / Kenya / Tanzania / Nigeria / Liberia / United Kingdom / /

Facility

University of Rome / Kilifi District Hospital / Open University / Blood Research Laboratory / Laboratory Procedures / John Radcliffe Hospital / Weatherall Institute of Molecular Medicine / Kenya Medical Research Institute / /

MedicalCondition

malaria disease / mild malaria / asymptomatic infections / ABSTRACT Background Malaria / clinical malaria / deļ¬ned malaria / both severe malaria / Incident malaria infections / rodent malaria / severe and complicated malaria / malaria infections / MS / infections / malaria / Plasmodium falciparum malaria / severe and fatal malaria / Sickle Cell Trait Thomas N. Williams1 / Sickle Cell Trait Patient Summary Background Sickle cell anemia / individual malaria infections HbAS / Malaria infection / fever / severe malaria / Plasmodium falciparum infection / sickle cell disease / individual infections / P. falciparum malaria / infection / mild clinical malaria / sickle cell trait / /

Organization

Nuffield Department of Clinical Laboratory Sciences / University of Rome / John Radcliffe Hospital / Open University / Weatherall Institute of Molecular Medicine / World Health Organization / London School of Hygiene and Tropical Medicine / Centers for Disease Control and Prevention / National Blood Transfusion Service / Kilifi District Hospital / Centre for Geographic Medicine Research / Kenya Medical Research Institute / Kenya Medical Research Institute National Ethical Review Committee / Nuffield Department of Medicine / Department of Paediatrics / /

Person

David J / Steve Bennett / Ann Trop Med / David Modiano / /

Position

Author / Academic Editor / Professor / Director / /

PublishedMedium

PLoS Medicine / /

Region

northern Liberia / western Kenya / /

Technology

alpha / electrophoresis / antibodies / http / genotype / /

URL

www.cdc.gov/genomics/hugenet/reviews/sickle.htm / www.plosmedicine.org / www.who.int/topics/malaria/en / /

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