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Endocrine system / Peptide hormones / Protein kinases / Growth factors / Mammalian target of rapamycin / Signal transduction / P70S6 kinase / Insulin-like growth factor 1 / AKT / Biology / Diabetes / Medicine


TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists
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Document Date: 2013-12-12 11:20:54

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Buffalo / Harris / /

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Gould / Iyer NV / Newman AB / RBS / AMD / Aiello LP / Rodriguez AE / Bryant KG / Kang SA / Tartis-Aging Inc. (USA) / Rosenzweig SA. / LG / Matsuda / Smith AG / Akulov AE / Hussong SA / Diabetes Prevention Program Research Group / Vinores SA / Creative Commons / Sousa AG / Macmillan Publishers Limited / /

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United States / /

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Product Issues / /

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Roswell Park Cancer Institute / Hall MN / /

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IndustryTerm

Prevention of diabetic complications and cancer / Prevention of beta-cell failure / Diabetes Care / treatment of age-related diseases / cancer prevention / clinical applications / therapy for patients with adult polycystic kidney disease / cancer treatment / Diabetes Prevention Program / /

MedicalCondition

ganciclovir-resistant cytomegalovirus infections / insulin-dependent diabetes mellitus / chronic overdosing / JE / acidosis / pneumococcal pneumonia / lymphoma cell growth / diabetic neuropathy / rather benevolent glucose intolerance / newonset blindness / Growth hormone receptor deficiency / melanoma / I insulin-dependent diabetes / starvation / chronic increase / p53 deficiency / tuberous sclerosis / obesity-linked insulin resistance / breast tumor / metabolic disorders / end-stage renal disease / hypoglycemia / hepatic insulin resistance / Kasuga M. Insulin resistance / II diabetes / early diffuse systemic sclerosis / undiagnosed disease / Tumor / diabetic retinopathy / cancer / advanced cancers / tumors / Parkinson disease / non-insulin-dependent diabetes mellitus / Mechanisms linking obesity / chronic treatment / human insulin resistance / carcinogenesis / hyperglycemia / Chronic / stroke / diabetes / Metabolic syndrome / viral infections / Liu T. Inflammatory / beta-cell retinopathy neuropathy systemic insulin resistance / diseases / diabetic macular edema / starvation diabetes / radiation-induced tumor / subependymal giant cell astrocytomas / renal failure / metastases / chronic hyperstimulation / factor-dependent retinal neovascularization / Comas M / J Diabetes Complications / adult-onset diabetes / diabetes complications / glucose intolerance / Endocr Relat Cancer / DF / chronic high-dose administration / true diabetes / sensorimotor peripheral neuropathy / hyperinsulinemia / heart dysfunction / chronic complications / insulinoma / either overt clinical diabetes / large-vessel occlusive disease / lethal prostate cancer / carcinoma / retinal and choroidal neovascularization / inflammatory cytokines / obesity / macrovascular disease / age-related diseases / blindness / I diabetes / insulin resistance / diabetic nephropathy / juvenile diabetes / Disease / atherosclerosis / diabetic complications / obesity-induced insulin resistance / insulin-mediated mammary tumor / rapamycin-induced insulin resistance / cardiovascular disease / prediabetes / hyperlipidemia / tumor necrosis / chronic effects / p53 tumor / myocardial infarction / then diabetes / tumor necrosis factor / heart failure / NIDDM / pathway-selective insulin resistance / adult polycystic kidney disease / diabetic kidney disease / Starvation Pseudo-Diabetes / Rapamycin-induced glucose intolerance / stroma increase cancer / retinal disorders / age-related disease / chronic high-dose rapamycin treatment / muscle insulin resistance / pancreatic insulin-secreting islet cell tumor / progressive hyperglycemia / /

MedicalTreatment

low-calorie diet / radiation / renal transplant / Chemoprevention / leg amputation / insulin therapy / Catheter / organ transplant / low calorie diet / /

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L3 / /

Organization

Medicare / Long-term administration / Department of Cell Stress Biology / US Federal Reserve / Internal Revenue Service / Chantelau E. Association / Roswell Park Cancer Institute / /

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Martin A. Gerosuppressant / Ann Neurol / Hee UmS / Carlton Streets / Van Roekel / Mol Med / Albert V / Elm Streets / P. Potential / Bennett J. Systemic / Van Obberghen / Arch Clin / T. Inappropriate / /

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VP / Brule / Antoch MP / Kannel WB / Major / Presley MP / Garrett BJ et al / Interest The author / *Corresponding author / consultant / Rozing MP / Houde VP / Hunter / /

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Pseudo / ganciclovir / glucose tolerance / recent-onset diabetes / mtor / /

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IR / New York / /

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PLoS One / /

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Joussen AM / Kuroki AM / Puzio-Kuter AM / /

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Neuroscience / radiation / apoptosis / alpha / ultrasound / transplantation / artificial intelligence / /

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www.nature.com/cddis / http /

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