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The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation Gabriel Leprivier,1 Marc Remke,2,3,4 Barak Rotblat,1 Adrian Dubuc,2,3 Abigail-Rachele F. Mateo,3,6 Marcel Kool,4 Sameer Agniho
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Document Date: 2013-06-04 12:58:00

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City

Cambridge CB21QP / Southampton SO171BJ / Paris / Iowa City / Heidelberg / Manchester M204BX / Vancouver / /

Company

AMP / Ge / Elsevier Inc. / ADP / /

Country

Germany / France / Canada / United Kingdom / /

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Event

Product Issues / FDA Phase / /

Facility

University of Iowa / University of British Columbia / University of Manchester / University Hospital Heidelberg / Vancouver Prostate Centre / Core Facility / University of Cambridge / University of Heidelberg / University of Toronto / University of Southampton / McGill University / Davis Research Institute / /

IndustryTerm

chemical inducers / energy-demanding process / Chemical inhibitors / energy response / energy / adaptation protocol / above adaptation protocol / energy balance / energy-consuming processes / energy sensor / media lacking glucose / /

MedicalCondition

primary human tumors / necrotic/total tumor / RasV12/ eEF2K tumors / control tumors / human tumor / murine tumors / human glioma subtypes / MEF tumors / chronic exposure / aggressive human brain tumors / eEF2K-overexpressing tumors / hypersensitivity / primary human MB tumors / both primary tumors / highly malignant adult brain tumor / common malignant brain tumor / RasV12 vector control tumors / human medulloblastoma / Cancers / Tumor / necrosis / significantly increased necrosis / Cancer / tumors / disease / eEF2K Protects Tumors / massive necrosis / RasV12/eEF2K+/+ MEF tumors / glioblastoma multiforme / apparent necrosis / MG63 osteosarcoma cells / RasV12/eEF2K tumors / highly resistant human tumor / Medulloblastoma / aggressive tumors / RasV12/eEF2K+/+ tumors / RasV12 control tumors / CR tumors / metastases / abnormal tumor / astrocytoma / oligodendroglioma / mixed glioma / MB tumor / primary tumor / /

MedicalTreatment

caloric restriction / /

Organization

Hospital for Sick Children / University of Heidelberg / National Institute of Health / Department of Pathology / Biostatistics German Cancer Research Center / Canada 7Goodman Cancer Research Centre / Institut Curie / USA 12Lady Davis Research Institute / Division of Neurosurgery / Department of Physiology / University of Cambridge / US Federal Reserve / University of Manchester / British Columbia Cancer Research Centre / Goodman Cancer Research Centre / University of Iowa / Sonia Labatt Brain Tumor Research Centre / Vancouver Prostate Centre / University of Southampton / McGill University / Montreal / University of Toronto / University of British Columbia / /

Person

Sonia Labatt / V. Peter Collins / Gabriel Leprivier / Arthur Labatt / Russell G. Jones / /

Position

conserved mediator / mediator / energy-demanding messenger / Representative / /

Product

eEF2K / AMPK activation / eEF2 Signaling We / /

ProvinceOrState

Alabama / North Dakota / British Columbia / Manitoba / Iowa / /

PublishedMedium

Molecular Biology / /

Technology

antibodies / siRNA / above adaptation protocol / Apoptosis / Gene expression / adaptation protocol / Neurosurgery / same adaptation protocol / 3G / /

URL

http /

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