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Fungal prions / Huntingtin / Chaperone / Amyloid / Polyglutamine tract / PolyQ / Plasmid / Prion / Trinucleotide repeat disorder / Biology / Proteins / Neurodegeneration


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Document Date: 2014-10-07 11:28:41

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City

The Sup35 PrD / Diamond / Boston / Berlin / Cambridge / /

Company

Mathworks Inc. / Nikon / Sigma Aldrich / 8D / Kochneva-Pervukhova NV / PerkinElmer / Fuji / /

Country

Germany / /

Currency

pence / /

/

Facility

Open Biosystems library / Howard Hughes Medical Institute / ORF library / gHoward Hughes Medical Institute / Whitehead Keck Microscopy Facility / Women’s Hospital / S.L. laboratory / Laboratory Medicine / Giorgini laboratory / Whitehead Institute / Massachusetts Institute of Technology / University of Pennsylvania / /

IndustryTerm

microfluidic device / oil immersion objective / liquid media / genetic tools / interaction network / reagents/analytic tools / computational algorithms / nonlinear least-squares fitting algorithm / proteostasis network / epifluorescence imaging / analysis software / juxtanuclear site / Long-term imaging / imaging / confocal imaging / automated imaging system / time-lapse and confocal imaging experiments / protein interaction network / time-lapse imaging / treatment of polyQ expansion diseases / 100× oil objective / /

MedicalCondition

neurodegenerative disease / polyQ expansion diseases / strain / Huntington’s disease / ORF / Huntington disease / von Hippel-Lindau tumor suppressor / human diseases / necrosis / disease / Each ORF / diseases / prevalent polyQ disease / neurodegenerative diseases / human disease / polyQ-expanded disease / /

Organization

Harvard Medical School / Eleanor Schwartz Charitable Foundation / Beckman Laser Institute Foundation / the University of Pennsylvania / Philadelphia / National Science Foundation / Perelman School of Medicine / dRenal Division / Max Delbrück Centre / Women’s Hospital / Massachusetts Institute of Technology / Helmholtz Association / Helmholtz Alliance for Mental Health / eMax Delbrück Center for Molecular Medicine / Biology and gHoward Hughes Medical Institute / Leila Y. Mathers Foundation / Ageing Society / European Union / Department of Pathology and Laboratory Medicine / Howard Hughes Medical Institute / Whitehead Institute for Biomedical Research / /

Person

Mai Tai / Jenny Russe / Ann Neurol / Kent E. S. Matlacka / A. S. Khalil / Susan Lindquist / William R. Hessea / Susan Lindquista / Erich E. Wankere / /

Position

Walker / Author / King / representative / /

Product

fs / IPOD / sorbitol / /

ProgrammingLanguage

MATLAB / C / D / ML / /

ProvinceOrState

New Mexico / Pennsylvania / South Carolina / Htt / Massachusetts / /

PublishedMedium

PLoS ONE / /

Technology

Bioinformatics / using Gateway technology / nonlinear least-squares fitting algorithm / antibodies / apoptosis / laser / prions / gene expression / spectroscopy / /

URL

www.pnas.org/cgi/doi/10.1073/pnas.1412504111 / www.pnas.org/cgi/content/short/1412504111 / www.pnas.org/lookup/suppl/doi / /

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