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Molecular biology / Dyes / Luminescence / Protein methods / Green fluorescent protein / Roger Y. Tsien / Directed evolution / Mutation / Fluorescence / Biology / Chemistry / Evolutionary biology


Evolution of new nonantibody proteins via iterative somatic hypermutation Lei Wang*, W. Coyt Jackson*, Paul A. Steinbach*, and Roger Y. Tsien*†‡ Departments of *Pharmacology and †Chemistry and Biochemistry and Howa
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Document Date: 2014-11-06 19:29:37


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City

La Jolla / Maennedorf / L. A. / Valencia / Petersen-Mahrt / San Diego / New York / /

Company

Qiagen / K. A. & Lukyanov S. A. / Merck / Palmer A. E. / GenBank / The times / Jenkins N. A. / /

Country

Switzerland / United States / /

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Facility

Howard Hughes Medical Institute / C terminus / University of California / /

IndustryTerm

integration site / optical imaging / oil / mineral oil / /

Organization

U.S. Department of Energy / Damon Runyon Cancer Research Foundation / National Academy of Sciences / Howard Hughes Medical Institute / Biochemistry and Howard Hughes Medical Institute / University of California at San Diego / /

Person

Arthur Weiss / Lei Wang / Shaughnessy / J. D. / Jr. / C. Qu / Paul A. Steinbach / Roger Y. Tsien / Nat / /

Position

representative / Harper / /

ProvinceOrState

Copeland / S. K. / New York / California / /

Technology

protein engineering / laser / directed evolution / antibodies / cloning / gel electrophoresis / Catalytic antibodies / /

URL

www.ncbi.nlm.nih.gov / www.pnas.org兾cgi兾doi兾10.1073兾pnas.0407752101 / /

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