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Cell biology / Filaggrin / Stratum corneum / Loricrin / Stratum granulosum / Epidermis / Corneocyte / Intermediate filament / Ichthyosis / Keratins / Biology / Anatomy


Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
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Document Date: 2015-02-19 08:33:20

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File Size: 2,65 MB

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City

San Francisco / New York City / Baltimore / /

Company

Ppl / AP1 / Macmillan Publishers Limited / /

Country

United States / /

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Event

Product Issues / /

Facility

New York University Cancer Institute / University of Maryland School / Center University of Maryland School / University of California / Veterans Affairs Medical Center / /

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IndustryTerm

lipid processing / incomplete processing / gene product / desmosome processing / incomplete postsecretory processing / reduced ceramide processing / transcription factor binding site / secreted lipid processing / /

MedicalCondition

harlequin ichthyosis / tumor / rare diseases / chronic proliferative dermatitis / parakeratosis / Disease / active infection / tissue inflammatory response / erythema / epidermal hyperplasia / epidermal genetic disorders / lamellar ichthyosis / infection / autosomal recessive congenital ichthyosis / inflammation / /

Organization

Department of Biochemistry and Molecular Pharmacology / 5The R.O. Perelman Department of Dermatology / New York University Cancer Institute / Department of Dermatology / 4Dermatology Service / Veterans Affairs Medical Center / University of California / San Francisco / Department of Microbiology and Immunology / University of Maryland School of Medicine / /

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Position

Prime Minister / USA *Corresponding author / /

Product

TAM67 / C5 / doxycycline / lipid barrier formation / mice / skin barrier / CE formation / /

ProvinceOrState

South Dakota / Maryland / California / /

PublishedMedium

Molecular Biology / /

Technology

alpha / antibodies / gene expression / apoptosis / /

URL

www.nature.com/cddis / /

SocialTag