Iron, α-synuclein and glial contributions in Parkinson’s disease Jun-Xia Xie* Institute of Brain Science and Disease, Qingdao University, Qingdao, 266071, China *Corresponding author E-mail: Ab

Source URL: scnw2018.cns.org.cn

Calcineurin determines toxic versus beneficial responses to α-synuclein Gabriela Caraveoa,b, Pavan K. Aulucka,c,1, Luke Whitesella, Chee Yeun Chunga, Valeriya Barua,b, Eugene V. Mosharovd, Xiaohui Yane, Manu Ben-Johnyf,

Source URL: lindquistlab.wi.mit.edu

• Peripheral membrane proteins
• Biochemistry
• Biology
• Chemistry
• Mechanistic target of rapamycin
• Signal transduction
• Neuroinflammation
• Alpha-synuclein
• Neurotoxin
• NFAT
• CA1
• MPTP

News Release Ramot at Tel Aviv University Ltd. Announces Licensing Agreement with Dexcel Pharma Technologies Ltd. Under the agreement, a new therapeutic strategy for Parkinson’s disease will be developed using a natur

Source URL: www.ramot.org

• Ehud Gazit
• Nanotechnologists
• Ramot
• Jerusalem
• Beta-synuclein
• Tel Aviv
• Alpha-synuclein
• Local government in Israel
• Chemistry

Aggregated α-synuclein intoxication of primary dopaminergic neurons as an in vitro model of Parkinson diseaseD. Buttigieg ; E. Gras-Lavigne ; M. Ouamer ; R. Steinschneider

Source URL: www.neuronexperts.com

• Neurotrophic factors
• Neurotoxins
• Pyridines
• Neurological disorders
• Peripheral membrane proteins
• Neurturin
• Neurodegeneration
• Alpha-synuclein
• GDNF family of ligands
• Glial cell line-derived neurotrophic factor
• Brain-derived neurotrophic factor
• Neuron

Research Award Laura Vopicelli-Daley, PhD University of Alabama at Birmingham Study Title: LRRK2 in Pathological Synuclein Transmission

Source URL: www.apdaparkinson.org

Research Award Talene Yacoubian, MD, PhD. University of Alabama at Birmingham Project Title: Effects of 14-3-3s on Alpha-synuclein Release and Toxicity

Source URL: www.apdaparkinson.org

RAPID COMMUNICATION Neuron-to-Neuron Transmission of a-Synuclein Fibrils Through Axonal Transport Eric C. Freundt, PhD,1* Nate Maynard, PhD,2 Eileen K. Clancy, PhD,1

Source URL: covert.stanford.edu

• Neuroscience
• Nervous system
• Biology
• Neurological disorders
• Neuroanatomy
• Neurophysiology
• Neurons
• Neurodegeneration
• Alpha-synuclein
• Lewy body
• Synucleinopathies
• Neuron

Background and Justification for The Parkinson’s Progression Markers Initiative Lead Biomarker Candidates Identified Lead PD Biomarker Candidates Alpha-Synuclein Rationale: The central role of alpha-synuclein in the pa

Source URL: www.ppmi-info.org

124 • The Journal of Neuroscience, January 4, 2012 • 32(1):124 –132 Neurobiology of Disease SIRT1 Protects against !-Synuclein Aggregation by Activating Molecular Chaperones

Source URL: glennfoundation.org

Research article Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease Christophe Lo Bianco,1,2 James Shorter,3 Etienne Régulier,2 Hilal Lashuel,2 Takeshi

Source URL: www.med.upenn.edu