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Muscular dystrophy / Transcription factors / RNA / GAL4/UAS system / Hypoxia-inducible factors / Dystrophin / Gene expression profiling / Duchenne muscular dystrophy / Heat shock protein / Biology / Gene expression / Genetics


Chronic Hypoxia Impairs Muscle Function in the Drosophila Model of Duchenne’s Muscular Dystrophy (DMD)
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Document Date: 2013-06-06 12:43:11

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File Size: 868,79 KB

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City

Santa Clara / AFFY / Carlsbad / Valencia / Gran Canaria / Philadelphia / Heidelberg / San Carlos / The AFFY / Foster City / Affymetrix GeneChipH / /

Company

Affymetrix / Qiagen / Creative Commons / Recreational Equipment Inc. / /

Country

Germany / United States / /

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Event

Product Issues / FDA Phase / /

Facility

Pennsylvania Muscle Institute / University of Tu¨bingen / University of Heidelberg / Institute of Physiology / University of Washington / Eye Hospital / HSP-HSF complex / University of Pennsylvania Microarray Core / University of Pennsylvania School / University of Las Palmas de Gran Canaria / /

IndustryTerm

dystrophin-like products / tango gene product / real time qPCR / molasses media / 4000F gas mixer / hypoxia protocol / /

MedicalCondition

muscular dystrophy / progressive myopathy / DMD disease / chronic exposure / United States of America Abstract Duchenne’s muscular dystrophy / muscle necrosis / muscle contraction / human diseases / Kyphoscoliotic deformities / tumor / necrosis / diaphragmatic dysfunction / disease / respiratory failure / muscle dysfunction / dystrophin deficiency / chronic hypoxia / Duchenne’s Muscular Dystrophy / respiratory insufficiency / deficiency / inflammation / /

NaturalFeature

Mount Denali/McKinley / Mount McKinley/Denali / Mount Denali/ McKinley / Mount Denali / Kahiltna Glacier / /

Organization

University of Pennsylvania School of Medicine / University of Heidelberg / Physiology and Pennsylvania Muscle Institute / Institute for Stem Cell and Regenerative Medicine / Centre for Ophthalmology / Muscular Dystrophy Association / the University of Pennsylvania / Institute of Physiology and Pathophysiology / Institute for Ophthalmic Research / Department of Physiology / National Park Service / University of Pennsylvania Microarray Core / Department of Biochemistry / University of Washington / Seattle / University of Tu¨bingen / /

Person

John B. West / Jose A. L. Calbet / /

Position

driver / original author / Editor / muscle-specific driver / Drosophila melanogaster model for DMD / dmDys vs. driver / Major / representative / reporter / /

Product

muscle / S1 / flies / /

ProvinceOrState

Washington / South Dakota / Pennsylvania / /

PublishedMedium

PLoS ONE / the PLoS ONE / /

Technology

alpha / Hypoxia protocol / CH protocols / apoptosis / PDF / laser / DNA Chip / gene expression / CH protocol / CG-RMA algorithm / genotype / Regenerative Medicine / /

URL

www.plosone.org / http /

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