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Barth syndrome / Cardiolipin / Mitochondrion / Sarcomere / Induced pluripotent stem cell / Mitochondrial disease / Cellular differentiation / Cell / British Thomson-Houston / Biology / Cellular respiration / Tafazzin


articles © 2014 Nature America, Inc. All rights reserved. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and
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Document Date: 2014-05-13 16:53:13

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File Size: 1,30 MB

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Dow Corning Midland / St. Paul / Austin / Stockholm / Natick / Redding / Amsterdam / Norwick / San Jose / Irvine / Polysciences / Newton / Boston / Baltimore / Scottsdale / Cambridge / Plainview / San Diego / /

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Life Technologies / Sheehy S.P. / Innovative Cell Technologies / 3M / Seahorses Biosciences / Jelight Company / Stemcell Technologies / BD Biosciences / Nature America Inc. / BT / Charles River Labs / Veeco Instruments / Olympus / 5Allele Biotechnology & Pharmaceuticals Inc. / F.S.P. / MicroChem Corp. / Fourier / BASF / /

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Netherlands / Sweden / Mali / United States / /

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pence / DKK / /

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Business Partnership / Product Issues / /

Facility

Scintillon Institute / WiCell Research Institute / Children’s Hospital of Philadelphia / Hospital Institutional Animal Care / Scale bar / University of Washington / Academic Medical Center / Harvard University / Hospital Institutional Review Board / Kennedy Krieger Institute / Laboratory of Genetic Metabolic Diseases / Boston Children’s Hospital / Stem Cell Institute / Hospital Institutional Care / Coriell Institute / /

IndustryTerm

heart-on-chip technologies / online version / cellular energy depletion / energy source / Gene replacement using modRNA technology / heart-on-chip / abnormal cardiolipin processing / lipid peroxidation product / High-energy phosphate stores / cellular energy deprivation / normal myocardial energy stores / Online Methods / heart-on-chip technology / printing / preserved cardiac high-energy phosphate levels / buffer solution / nuclear magnetic resonance imaging / medicine ONLINE METHODS / advance online publication / microcontact printing / /

MedicalCondition

TAZ deficiency / Teratomas / teratoma analysis / contractile dysfunction / Twitch / ischemic heart disease / BTHS myopathy / BTHS cardiomyopathy / cardiac dysfunction / effectively model disease / iPSC disease / Barth syndrome / mitochondrial dysfunction / cardiomyopathy / cardiolipin deficiency / ischemic and hypertensive heart failure / BTHS contractile dysfunction / cardiomyopathies / skeletal mitochondrial myopathy / mechanical dysfunction / infection / monogenic mitochondrial cardiomyopathies / mitochondrial cardiomyopathy / adult severe combined immunodeficiency / disease / contraction / familial dilated cardiomyopathy / mitochondrial disorder / myocardial infarction / familial hypertrophic cardiomyopathy / heart failure / human disease / /

NaturalFeature

MT LA / /

Organization

Coriell Institute for Medical Research / Scintillon Institute / Boston Children’s Hospital Institutional Care and Use Committee / LA V / MLCL / Abnl Normalized / Boston Children’s Hospital Translational Investigator Service / NS NS / MT V / African Union / LA BE / Academic Medical Center / University of Washington / Seattle / Children’s Hospital of Philadelphia / Harvard Medical School / Division of Genetics / National Institute of Health / Institute for Stem Cell and Regenerative Medicine / Harvard University / Kennedy Krieger Institute / Center for Cardiovascular Biology / Institutional Review Board of the Children / Laboratory of Genetic Metabolic Diseases / Boston Children’s Hospital Institutional Animal Care and Use Committee / Boston Children’s Hospital / WiCell Research Institute / Sarcomeric / Normalized / Barth Syndrome Foundation / School of Engineering and Applied Sciences / 13Harvard Stem Cell Institute / Stem Cell Institute / 2Wyss Institute / Boston Children’s Hospital Institutional Review Board / Sarcomere / /

Person

Francesco Silvio / Nat / Stoney / Kevin Kit / Ted Pella / /

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Position

D.J. / AUTHOR / representative / model for familial dilated cardiomyopathy / messenger / Fisher / /

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doxycycline / Cas9 / modRNA technology4 / 7 / 15 / sarcomere assembly / /

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Louisiana / Washington / Nova Scotia / California / Maryland / Warrington / Massachusetts / /

PublishedMedium

Molecular Biology / PLoS ONE / /

Technology

stem cells / human genome / Biomaterials / tissue engineering / magnetic resonance imaging / gene expression / spectroscopy / heart-on-chip technology / genotype / 3g / heart-on-chip technologies / CAT / MTF chips / alpha / Gene replacement using modRNA technology / antibodies / Biotechnology / lithography / laser / OCR / PDMS-coated chips / Lab Chip / Regenerative Medicine / /

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