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1442 Determinants of Demethylation and Clinical Response In AML Patients Treated With SGI-110, a Novel Subcutaneous (SQ) Hypomethylating Agent (HMA) In a Phase 1 Study Woonbok Chung, PhD1, Pietro Taverna, PhD2, John F L
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City

Philadelphia / Dublin / Cambridge / Houston / /

Company

2Astex Pharmaceuticals Inc. / Johnson and Johnson / Pharmaceuticals Inc. / Astex Pharmaceuticals / /

Country

United Kingdom / /

Currency

pence / /

Event

FDA Phase / /

Facility

Temple University / University Hospital / The University of Texas MD Anderson Cancer Center / MD1 Institute / /

MedicalCondition

Leukemia / /

MedicalTreatment

chemotherapy / /

Organization

5Temple University Hospital / MD1 Institute for Cancer and Molecular Biology / Temple University / Philadelphia / University of Texas / /

Person

Yong Hao / Jean Pierre Issa / John F Lyons / Pathogenic Characteristics / Patricia Kropf / Mohammad Azab / /

Position

Representative / /

Product

SGI-110 / /

ProvinceOrState

Texas / Pennsylvania / California / /

PublishedMedium

Molecular Biology / /

Technology

Gene expression / chemotherapy / pharmacodynamics / /

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