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This article was published in an Elsevier journal. The attached copy is furnished to the author for non-commercial research and education use, including for instruction at the author’s institution, sharing with colleag
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Document Date: 2015-04-27 23:20:27


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Seattle / Tokyo / /

Company

AIDS Clinical Trials Group / Puget Sound Partners / Kohler / Elsevier Ltd. / J. Pharm / /

Country

Thailand / United States / Uganda / Botswana / /

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pence / USD / /

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Event

FDA Phase / /

Facility

National Library of Medicine’s / University of Washington’s / University of Washington / The University of Washington / /

IndustryTerm

treatment of complex diseases / active site / treatment of human diseases / energy minimization / multitarget inhibitor discovery protocol / drug discovery protocol / computer processing capabilities / comparable chemical environments / large regulatory systems / pharmaceutical / molecular dynamics algorithm / food / HIV treatment / pharmaceutical screens / chemical structure similarity / evolutionary chemical context / treatment of HIV / even tiny chemical changes / catalytic site / model systems / systematic chemical group perturbations / chemical / in vivo systems / energy transmission / /

MedicalCondition

HIV / acquired immune deficiency syndrome / high dissociation / several diseases / Hepatitis C / Hepatitis B / pulmonary / human diseases / myocarditis / infections / infectious agents / Alzheimer’s disease / cancer / opportunistic infections / disease / opportunistic pathogen infections / chronic / complex diseases / Plasmodium falciparum infections / histoplasmosis / malarial parasite P. falciparum infection / Polio / opportunistic infection / complex drug-resistant diseases / chronic disease / diseases / AIDS / infectious diseases / associated opportunistic pathogen infections / infection / complex human diseases / Vaccinia / infectious disease / /

MedicalTreatment

antiretroviral treatment / antibiotics / chemotherapy / immunosuppression / HAART / /

Organization

Biotechnology / National Science and Technology Developmental Agency / University of Washington / National Institute of Health / Food and Drug Administration / National Science Foundation / School of Dentistry / Department of Microbiology / Department of Oral Biology / School of Medicine / Department of Medicine / USA National Center for Genetic Engineering and Biotechnology / /

Person

Renee Ireton / Nat / Roger Bumgarner / Brady Bernard / Michael Lagunoff / Al Omari / Murry / /

Position

G.P. / Physician / General / Corresponding author / author / Private / author for non-commercial research / http /

Product

zidovudine / miconazole / Cotrimoxazole / Gleevec / Cyclosporine / clotrimazole / Cosalane / isoniazid / pyrazinamide / Amphotericin B / nystatin / HIV-1 / Glossary Drug / screening / Screening compounds / experimental drug / /

ProvinceOrState

Washington / /

PublishedMedium

Elsevier / /

Technology

alpha / drug metabolism / Bioinformatics / Genetic Engineering / molecular modeling / X-ray / Biotechnology / high-throughput screening / Computational chemistry / search engine / multitarget inhibitor discovery protocol / molecular dynamics algorithm / pharmacokinetics / chemical libraries / second-generation protocol / drug discovery / Pharmacogenetics / drug discovery protocol / gene expression / chemotherapy / web server / drug development / /

URL

http /

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