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Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase
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United States / Lebanon / /

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University of Toronto / Dartmouth College / /

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coexpression-based influence networks / weighted bidirectional networks / undirected weighted networks / pharmaceutical industry / influence networks / carrier protein / protein networks / regulatory gene network / biological systems / cancer therapeutics / untreated tumor network / cancer treatment / method to coexpression networks / undirected interaction networks / coexpression network / undirected weighted coexpression networks / gene-products / directed regulatory networks / coexpression networks / undirected coexpression networks / biological networks / treatment of breast cancer / treatment of cancer / influence network / treatment of ER+ breast cancers / gene regulatory networks / igraph software / directed weighted influence networks / online submission / breast tumor coexpression networks / /

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ovarian cancer / patient tumors / untreated tumor / untreated ER+ breast tumors / novel cancer / J Cancer / coexpression-based influence networks representing ER+ breast tumors / ER+ breast tumor / breast tumor / MS / Breast cancer / tumor / mitochondrial dysfunction / breast cancers / ER+ breast cancers / individual tumors / cancer / tumors / disease / progesterone receptor-positive breast cancer / progesterone receptor positive breast cancer / human cancer / ER+ breast cancer / residual tumors / operable breast cancer / BMC Cancer / ER+ breast tumors / untreated tumors / influence network representing untreated ER+ breast tumors / /

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endocrine therapy / chemoprevention / neoadjuvant treatment / cancer therapeutics / /

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National Institute of Health / Geisel School of Medicine / Institute for Quantitative Biomedical Sciences / Dartmouth College / Department of Genetics / HB7937 One Medical Center / Department of Pharmacology and Toxicology / FDA / University of Toronto / /

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Van Gogh-Like / Anna C. Greene / /

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Walker / Krzyzanowski PM / player / author / Lisanti MP / Fisher / /

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letrozole / GLRX2 / /

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New Hampshire / /

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Complex Systems / /

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Genomics / Bioinformatics / apoptosis / single nucleotide polymorphism / drug discovery / DNA Chip / Gene expression / drug development / resisting apoptosis / /

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