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The Journal of Neuroscience, November 10, 2010 • 30(45):15165–15174 • Neurobiology of Disease TRPA1 Contributes to Cold Hypersensitivity Donato del Camino,1 Sarah Murphy,1 Melissa Heiry,1 Lee B. Barrett,4 Ta
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Document Date: 2010-11-16 11:52:17

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Hydra Biosciences Inc. / Malmberg AB / Sigma-Aldrich / Proc Natl Acad Sci U S A / Cox / Magdalene M. Moran1 Hydra Biosciences Inc. / Kane SA / Dubin AE / Siemens / /

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Massachusetts General Hospital / Memorial Drive / Children’s Hospital / The Scripps Research Institute / /

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The collagenase solution / reactive chemicals / chemical damage / bath solutions / mustard oil / chemical agonists / reactive chemical / chemical agonist / pipette solution / perfusion solutions / external solution / chemical nociception / perfusion systems / bath solution / /

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hyperalgesia / acute local inflammation / mechanical hypersensitivity / both neuropathic and inflammatory pain states / tissue injury / induced cold hypersensitivity / CFA-induced cold hypersensitivity / mechanical hyperalgesia / Mechanical hyperalgesia data / HNE also induced heat hyperalgesia / persistent inflammation / dorsal root ganglion / peripheral inflammatory and neuropathic pain / cold hypersensitivity / nerve injury / inflammatory and neuropathic pain / potent pulmonary irritant / profound TRPA1-dependent cold hypersensitivity / mechanical and cold hyperalgesia / Spared nerve injury / pain / thermal hyperalgesia / pulmonary irritant acrolein / heat hyperalgesia / inflammation / cold hyperalgesia / Thermal hyperalgesia data / neurogenic inflammation / inflammatory responses / localized inflammation / inflammatory actions / /

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Harvard Medical School / Department of Cell Biology / Institutional Animal Care and Use Committee / Department of Anesthesia and Critical Care / Department of Neurobiology / Massachusetts General Hospital / Children’s Hospital Boston / Novartis Research Foundation / Department of Anesthesia / 2Genomics Institute / Montana MC / EPC / Kirby Neurobiology Center / US Federal Reserve / Scripps Research Institute / Society for Neuroscience Policies / /

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Xiaoguang Zhen / David Kimball / Donato del Camino / Kwan / Timothy Strassmaier / Jennifer Monsen / Alexis Biochemicals / David Clapham / David P. Corey / /

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