| Document Date: 2011-08-18 06:00:11
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City Ellisville / Mannheim / Rhein / Fremont / Darmstadt / Hamburg / Wu¨rzburg / Pasching / Friesoythe / Santa Cruz / / Company Cell Signaling Technologies / Merck / Millipore / Macmillan Publishers Limited / / Country Germany / United States / / / Facility University Hospital Wu¨rzburg / TRAIL Abbreviations / University of Tu¨bingen / IKK complex / / IndustryTerm proteolysis/processing / p100 processing / downstream p100 processing effect / appreciable p100 processing / / MedicalCondition tumor / necrosis / cancer / multiple myeloma / Disease / refractory multiple myeloma / progressive disease / tumor necrosis / Experimental Medicine Multiple myeloma / Disease metastasis / multiple myeloma cell lines / / Organization Division of Molecular Internal Medicine / Division of Hematology / Department of Internal / University of Tu¨bingen / / Person K. Schulze-Osthoff / / / Position high producer / Germany *Corresponding author / operative / / Product TNFR1 / Enbrel / FlagTNF(32W/86T) / / Technology alpha / antibodies / Biotechnology / gene expression / gel electrophoresis / apoptosis / / URL www.nature.com/cddis / /
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TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms