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Signal transduction / Immune system / Apoptosis / Fas receptor / Fas ligand / Caspase 3 / Death effector domain / Crosstalk / Mitogen-activated protein kinase / Biology / Cell biology / Programmed cell death


Citation: Cell Death and Disease[removed], e212; doi:[removed]cddis[removed] & 2011 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Caspase-8 activity has an essential role in
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Document Date: 2011-10-06 05:59:45

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City

Rodgau / Frankfurt/Main / Langenselbold / Freiburg / Mainz / Heidelberg / Mannheim / Wetzlar / Steinheim / Darmstadt / /

Company

Leica Microsystems / Life Technologies / Southern Biotechnology Associates / Sigma-Aldrich / Amersham / CD95 / Merck / Creative Commons / PerkinElmer / Macmillan Publishers Limited / /

Country

Germany / United States / /

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Facility

NH2 terminus / University of Heidelberg / /

IndustryTerm

live cell imaging / incomplete processing / active procaspase-8a/b cleavage products / cleavage products / cleavage product / procaspase-8a/b cleavage products / reduced processing / imaging / oil immersion lens / procaspase-8a/b processing / chemicals / autocatalytic processing / /

MedicalCondition

MS / apoptosis-resistant tumor / tumor / cancer / Disease / diseases / /

Organization

University of Heidelberg / German Cancer Research Center / Institute for Pharmacy and Molecular Biotechnology / Helmholtz Alliance on Systems Biology / Institute for Pharmacy / DED / Division of Immunogenetics / /

Person

Yang X. Interdimer / Nevertheless / /

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Position

representative for four independent experiments / caspase activation model for receptor-induced apoptosis / Harper / model / Major / Representative / Germany *Corresponding author / /

Product

Leica SP2 / C20 / HeLa / HeLa-CD95 / /

PublishedMedium

Molecular Biology / /

Technology

Bioinformatics / antibodies / siRNA / Biotechnology / apoptosis / Cell Signaling Technology / laser / Functional Genomics / gene expression / condensation / http / simulation / /

URL

http /

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