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Apoptosis / Proteins / Immune system / Heat shock proteins / Hsp90 / Fas receptor / Caspase 3 / TRAIL / Tumor necrosis factor-alpha / Biology / Cell biology / Programmed cell death


OPEN Citation: Cell Death and Disease[removed], e1666; doi:[removed]cddis[removed] & 2015 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis
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Document Date: 2015-02-26 08:32:57


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File Size: 1,13 MB

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City

South San Francisco / Amsterdam / San Jose / St. Louis / Worcester / Minneapolis / Washington / DC / Chicago / Cambridge / /

Company

SPSS Inc. / HSP90 / GraphPad Software Inc. / Genentech / Leidos Biomedical Research Inc. / Kreatech Diagnostics / BD Biosciences / National Academy Press / Charles River Laboratories Inc. / Frederick National Laboratory / Ligand / Molecular Targets Laboratory / Ford / Cox / Creative Commons / Damu AG / Macmillan Publishers Limited / CambridgeSoft Corp. / /

Country

Netherlands / United States / /

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Event

FDA Phase / /

Facility

TRAIL sensitizers / 1 / 6 / 8 / 10 / 16 / 17 / Frederick National Laboratory / Clark University / HSP90 complex / Medium TRAIL / Walczak H. Getting TRAIL / TRAIL DISC.38 Thus / NIH Pharmacy / Laboratory Animals / TRAIL signaling / 33 / 41 / 42 / /

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IndustryTerm

covalent chemical adduct / cancer therapy / software version / cell culture media / therapy of autoimmune diseases / Chemical structures / natural product / natural products / chemical reactivity / therapeutic applications / /

MedicalCondition

successful cancer / detectable palpable tumor / human renal carcinoma / resistant MET-driven tumor / toxic liver injury / renal carcinoma lines / glioblastoma cells / human tumor / human melanoma / injury / leukemia / tumor / mitochondrial dysfunction / cancer / tumors / several TRAIL-resistant cancer / subcutaneous tumors / complete and sustained tumor / glioblastoma cell lines / human cancer / renal carcinoma / malignant melanoma / breast tumors / human hepatocellular carcinoma / human renal cancer / human glioma / long-term tumor / diverse cancer / Wu C-C. Withanolides-induced breast cancer / neoplastic disease / human renal cell carcinomas / refractory hematologic malignancies / MS / human breast cancer / pancreatic cancer / autoimmune diseases / programmed necrosis / otherwise resistant cancer / Disease / tumour / ACHN renal cancer / tumor necrosis / several TRAIL-resistant melanoma / primary human astrocytoma cells / resistant cancer / Mol Cancer / heat shock / /

MedicalTreatment

cancer therapy / chemotherapy / /

NaturalFeature

Marron MT / /

Organization

National Research Council / World Health Organization / US Government / Center for Cancer Research / Intraperitoneal administration / Frederick National Lab / Cancer Research Animal Care and Use Committee / National Institute of Health / Laboratory for Cancer Research / Department of Health and Human Services / Clark University / /

Person

Avi Ashkenazi / Crystal Violet / Larue L et al. Withaferin / /

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Position

driver / USA *Corresponding author / /

Product

Sigma / Olympus E 20 Headphone/Headset / Logan / nitro / PS-341 / /

ProgrammingLanguage

C / /

ProvinceOrState

California / South Dakota / /

PublishedMedium

Cancer Research / PLoS One / /

Technology

Lifeline Cell Technology / siRNA / High-throughput screening / apoptosis / gene expression / chemotherapy / treating cancer / 3g / antibodies / /

URL

http /

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