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Carcinogenesis / Grading / Pathology / Breast cancer / Cellular differentiation / TGF beta 1 / Metastatic breast cancer / UCP2 / Carcinoma / Medicine / Biology / Oncology


Citation: Cell Death and Disease[removed], e53; doi:[removed]cddis[removed] & 2010 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis Negative regulation of UCP2 by TGFb signaling
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Document Date: 2010-07-20 01:47:35


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City

San Francisco / Minneapolis / Santa Cruz / /

Company

IgG / California Pacific Medical Center / Macmillan Publishers Limited / /

Country

United States / /

Currency

pence / /

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Event

Product Issues / FDA Phase / /

Facility

California Pacific Medical Center Research Institute / Stanford University / Campus Drive / /

IndustryTerm

live cell imaging / start site / chemical uncoupler / live model systems / energy / breast cancer model systems / transcriptional start site / gene product / confocal imaging / energy dissipation / time-lapse imaging / live confocal imaging / /

MedicalCondition

thereby promoting tumor / high histological-grade tumors / novel breast cancer / primary breast cancer / low and intermediate-grade primary breast cancer A Sayeed1 / thereby augmenting tumor / UCP2-KD tumor / poorly differentiated tumor / intermediate-grade primary breast cancer / clinical disease / poorly differentiated breast cancer / metastatic breast cancer / responsive tumor cells / breast tumor / such tumors / high-grade breast cancer / primary breast tumor / Methods Primary breast carcinoma / human breast cancer / breast cancer / primary tumors / poorly differentiated tumors / tumor / mitochondrial dysfunction / Although cancer / cancer / UCP2-transduced tumor / UCP2-negative tumors / tumors / Disease / thereby enhancing tumor / Negative tumors / siRNA-transfected tumor / formalin-fixed primary breast cancer / solid tumor / high-grade tumor / particularly promising tumor / full-sized tumor / UCP2 overexpressing tumor / negaitive tumors / aggressive tumor / breast tumors / tumor cells / TGFb-resistant high-grade tumors / cases Positive tumors / moderately differentiated breast tumors / improved disease / intermediate-grade tumors / live tumor / primary tumor / /

Organization

Department of Chemical and Systems Biology / Stanford University / California Pacific Medical Center Research Institute / /

Person

Alexa Fluor / /

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Position

USA *Corresponding author / representative / /

Product

M-16 / UCP2 / cell differentiation / C20 / /

ProvinceOrState

California / /

SportsLeague

Stanford University / /

Technology

siRNA / Biotechnology / apoptosis / gene expression / supplier-recommended protocol / /

URL

www.nature.com/cddis / /

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