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Proteins / Apoptosis / Neurological disorders / Organelles / Unfolded protein response / Apoptosome / Neurotoxicity / Neurodegeneration / Binding immunoglobulin protein / Biology / Cell biology / Programmed cell death


Hindawi Publishing Corporation ISRN Cell Biology Volume 2013, Article ID[removed], 22 pages http://dx.doi.org[removed][removed]Review Article
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Document Date: 2014-08-14 11:06:00

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File Size: 2,60 MB

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Company

Creative Commons / Hindawi Publishing Corporation / /

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Event

Product Issues / FDA Phase / /

Facility

University of Coimbra / Neurodegenerative Diseases Cláudia M. F. Pereira Center / IP3 R/GRP75/VDAC complex / scaffold SAP102 / /

IndustryTerm

subsequent processing / regulated signaling network / mitochondrial energy production / secretory carrier membrane protein / protein quality control systems / chemical inhibition / protein quality control machinery / chemical chaperone-like activity / mitochondrial network / contact site / therapeutic applications / mitochondrial respiratory chain / /

MedicalCondition

Pick’s disease / numerous human conformational disorders / aggregates/inclusions Alzheimer’s disease / scrapie prion protein / autosomal dominant neurodegenerative disorder / several neurodegenerative diseases / ALS / several tauopathies / Huntington’s disease / prion disease / Amyotrophic Lateral Sclerosis / natural and experimental prion diseases / progressive cognitive impairment / ataxia / psychiatric problems / protein misfolding disorders / increasingly prevalent disorders / related tauopathies / neuronal dysfunction / proteasome dysfunction / mouse model mimicking CJD / apparent memory dysfunction / nigra Cytoplasmatic Amyotrophic Lateral Sclerosis / dissociation / different tauopathies / frontotemporal lobar degeneration / SK-NSH human neuroblastoma cells / tauopathies / ER dysfunction / significantly attenuated disease / mitochondrial dysfunction / Alzheimer’s disease / conformational disorders / parkinsonism / disease / proteasomal dysfunction / human teratocarcinoma cell line / CJD / progressive supranuclear palsy / both infectious and familial prion diseases / prion-related disorders / Tau Extracellular Cytoplasmatic Parkinson’s disease / Protein Misfolding Neurodegenerative Diseases Neurodegenerative disorders / neuroblastoma cells / chronic administration / transmissible spongiform encephalopathies / prion diseases / dementia Dementia / common neurodegenerative disorder / rare and fatal diseases / murine scrapie / sarcoma / sporadic tauopathies / Creutzfeldt Jakob disease / VAPB Huntington’s disease / frontotemporal dementia / Parkinson’s disease / diseases / chronic and progressive neurodegenerative disorder / prevalent diseases / familial Alzheimer’s disease / memory deficits / neurodegenerative diseases / deficiency / inflammation / genetic prion diseases / familial prion diseases / disorders / /

Organization

University of Coimbra / Faculty of Medicine / Neurodegenerative Diseases Cláudia M. F. Pereira Center for Neuroscience and Cell Biology / Cell Biology / Systemic administration / /

Person

D. Arnoult / A. Colanzi / E. Meacci / A. Hergovich / /

Position

mediator / /

Product

LG PC12 Radio / paclitaxel / Taxol / CA1 / chronic ER stress / mice / ER Ca2+ homeostasis / homeostatic regulation / /

ProvinceOrState

Montana / /

Technology

alpha / Neuroscience / siRNA / apoptosis / prions / Gene expression / CAD / /

URL

http /

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