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P-glycoprotein / ATP-binding cassette transporter / Multiple drug resistance / Chemotherapy / Breast cancer / Prostate cancer / Discovery and development of tubulin inhibitors / Medicine / ABC transporters / Biology


© 2000 Nature America Inc. • http://biotech.nature.com DISEASES Cancer multidrug resistance
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Document Date: 2002-10-10 10:47:54

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City

San Francisco / Seattle / Slough / Redwood City / Cambridge / Diego / City / Ramon / San Diego / /

Company

CytRx / Isis Pharmaceuticals / SuperGen / Cell Therapeutics / Cole S.P. / Biochem Pharma / Genetix Pharmaceuticals / Vertex / Titan Pharmaceuticals / Nature America Inc. / Immunex / /

Country

United States / Canada / United Kingdom / /

Event

FDA Phase / /

IndustryTerm

oligonucleotide combinatorial technology / energy-dependent pump / treatment of patients with chemorefractory cancers / treatment of drug-resistant breast cancer / antisense technology / /

MedicalCondition

ovarian cancer / resistant cancers / lower gastrointestinal tract cancers / solid tumors / multidrug resistant cancers / small cell lung cancer / thus allowing cancer / acute leukemia MDR / gastrointestal tumor / refractory ovarian cancer / surprisfrom cancer / prostate cancer / II clinical trials targeting breast cancer / cancers / leukemia / tumor / cancer / Tumors / disease / important cancer / blood cancers / soft tissue sarcoma / drug-resistant breast cancer / chemorefractory cancers / such a non-small cell lung cancer / aggressive disease / lung cancer / sarcomas / sarcomas MDR / metastases / primary tumor / /

MedicalTreatment

Genetic Therapy / chemotherapy / gene therapy / /

OperatingSystem

Isis / /

Person

Gene Ther / /

Product

etoposide / paclitaxel / IT18 / Incel / MDR-18 / /

ProvinceOrState

Quebec / /

PublishedMedium

Nature Biotechnology / /

Technology

combinatorial chemistry / pharmacogenomic / oligonucleotide combinatorial technology / antisense technology / antibodies / BIOTECHNOLOGY / high-throughput screening / stem cells / gene therapy / drug discovery / chemotherapy / /

URL

www.biovista.com / http /

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