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Cell biology / Cell signaling / Peptide hormones / Uridine diphosphate N-acetylglucosamine / O-linked glycosylation / Phosphoinositide 3-kinase / Insulin receptor / AKT / Phosphorylation / Biology / Posttranslational modification / Protein kinases


O-GlcNAc signaling: a metabolic link between diabetes and cancer?
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Document Date: 2014-05-16 22:13:38


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File Size: 453,60 KB

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City

Baltimore / /

Company

Checkpoint / AMP / Lehman / Caldwell S.A. / Whelan S.A. / Elsevier Ltd. / /

Country

United States / /

Currency

USD / /

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Facility

C terminus / checkpoint Review Trends / Hart laboratory / /

IndustryTerm

mass spectrometry site / energy imbalance / energy / energy production / high energy donor substrate / serine phosphorylation site / final product / chemical/enzymatic tagging / phosphorylation site / cellular energy / main energy source / energy metabolism / metabolic networks / enzymatic product / proline-directed phosphorylation site / /

MedicalCondition

profound insulin resistance / Both diabetes / multiple myeloma / chronic renal failure / electron transfer dissociation / solid tumors / primary breast carcinomas / heart disease / chronic stress / Both diseases / hepatic insulin resistance / breast cancer / cancers / tumor / chronic hyperglycemia / Insulin resistance / Alzheimer’s disease / cancer / tumors / disease / metabolic diseases / Burkett lymphoma / hyperglycemia / Chronic / cervical carcinoma / cardiovascular disease / diabetes / glucosamine-induced insulin resistance / lymphomas / metabolic syndrome / hyperinsulinemia / lower glucose disposal rates / metastatic tumors / both hyperglycemia / diabetes mellitus / diseases / collision-induced dissociation / NIDDM / aggressive tumors / metabolic disorder / metastatic murine tumor / chronic nutrient excess / Is cancer / heat shock / /

MedicalTreatment

bypass / /

Organization

pentagon / Internal Revenue Service / Department of Biological Chemistry / The Johns Hopkins University School of Medicine / Medicare / US Federal Reserve / /

Person

Nat / /

Position

phosphorylCorresponding author / Marshall / /

Product

adenosine / /

ProvinceOrState

Copeland / Aurora / Maryland / /

PublishedMedium

PLoS One / /

Technology

Genomics / Proteomics / siRNA / metabolic networks / cloning / DNA binding / UDP / single nucleotide polymorphism / gene expression / http / initiated resulting in altered gene expression / /

URL

www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf / /

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