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Molecular biology / Molecular genetics / Gene delivery / Sense / RNA interference / Vectors in Gene Therapy / Cell-penetrating peptide / Oligonucleotide / Gene expression / Biology / Genetics / RNA


Current Drug Delivery, 2011, 8, [removed]Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions Mahmoud Elsabahy1, Adil Nazarali2 and Marianna Foldvari1,*
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Document Date: 2014-10-27 09:22:56


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City

Wettig / De Smedt / Mahato / Semple / Wong / Wakefield / Saskatoon / Yew / Klimuk / Ingolia / Pandey / L.A. / /

Company

Nucleonics Inc. / Lawton A.E. / Wolfe S.A. / Bentham Science Publishers Ltd. / Bernstein / Toyota / Santaris Pharma / Hanson / AON / J. Pharm / Smith A.E. / Isis Pharmaceuticals Inc / Rao D.D. / ABC / Barros S.A. / Ge / Russell / Shimizu / Opko Health / /

Country

Canada / United States / /

Currency

USD / /

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Event

Product Issues / FDA Phase / /

Facility

Virchows Arch / Plant Biol / College of Pharmacy / University of Saskatchewan / University of Waterloo / RISC complex / Drosha complex / Cmethylene bridge / /

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IndustryTerm

nucleus-targeting gene delivery systems / protein product / microRNA processing / cancer therapeutics / treatment of several diseases / chemical modification analysis / delivery systems / translation machinery / chemical structures / target site / treatment of viral infections and cancer / nucleic acid-based products / treatment of cancer / therapeutics for cancer / human plasmid products / clinical applications / gene delivery systems / delivery technologies / genetic products / chemical enhancers / cancer treatment / non-viral delivery systems / nucleic acid products / aqueous glucose solution / stepwise processing / carrier type / recognition site / gene-therapy products / siRNA delivery systems / non-viral systems / chemical stability / veterinary applications / correct processing / precision tools / gene delivery applications / therapeutic applications / enzymatic machinery / chemical modifications / /

MedicalCondition

inflammatory reactions / pulmonary delivery / viral infection / intracellular dissociation / e.g. tumors / dermatological diseases / hepatitis B / lethal viral infection / systemic inflammatory reactions / pulmonary gene expression / human diseases / tumor / cancer / hepatoma cells / viral infections / diseases / deficiency / inflammatory effects / nasal and pulmonary antigen / CpGmediated inflammatory response / siRNA-based cancer / several diseases / hepatitis C / roux sarcoma virus / inflammatory cytokines / metastatic tumor / M.C. Cancer / reduced inflammation / severe inflammation / chronic hepatitis B / human disease / /

MedicalTreatment

vaccination / gene-therapy / chemotherapy / Gene therapy / dendrimer / vaccinations / cancer therapeutics / dendrimers / Adjuvant therapy / /

OperatingSystem

Isis / /

Organization

College of Pharmacy / College of Pharmacy and Nutrition / Natural Sciences and Engineering Research Council of Canada / University of Waterloo / School of Pharmacy / University of Saskatchewan / /

Person

Nat / Kim / Hyde / Kim / V / J. Gene Med / E. Gene / Madden / Gene Med / /

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Position

T.D. / author / King / Dean / Marshall / Judge / /

Product

Tao / Bentham Science Publishers Ltd. 236 Current Drug / RNAi / M-9 / folic acid / nucleic / LifeTide® SW / B1000 / SPC3649 / gene Induce immunity / genes / /

ProgrammingLanguage

R / /

ProvinceOrState

Saskatchewan / New Mexico / Rhode Island / South Carolina / Nova Scotia / Northern Territory / S.K. / South Dakota / /

PublishedMedium

Soft Matter / Molecular Biology / /

Technology

siRNA / antisense molecules / delivery technologies / Drug Delivery / Biomaterials / gene expression / chemotherapy / gene delivery system / Antisense technologies / DNA delivery / antibodies / Hybridization / gene therapy / pharmacokinetics / gene delivery / /

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