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Biotechnology / Genetics / Applied genetics / Zinc finger nuclease / Green fluorescent protein / Plasmid / Viral vector / Recombinase-mediated cassette exchange / Genome engineering / Biology / Molecular biology / Gene delivery


© 2007 Nature Publishing Group http://www.nature.com/naturebiotechnology ARTICLES Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector
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Document Date: 2013-07-19 16:33:23


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City

Ozzano Emilia / A100 Richmond / Helsinki / Baltimore / Cremona / Milan / Montre´al / /

Company

Lg / C.F. III & Chow S.A. / Sangamo BioSciences / McDermott / Bentley S.A. / Thomson / QIAGEN / D. Melton / Becton Dickinson / Cambrex / RT 7 No RT / 3Sangamo BioSciences Inc. Pt / CHU Ste-Justine 3175 Co / Amersham Biosciences / 4Reproductive Technologies Laboratory / /

Country

Italy / United States / Canada / /

Currency

pence / cent / PGK / /

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Event

Product Issues / /

Facility

Raffaele Telethon Institute / Canal Blvd. / Harvard Stem Cell Institute / Scale bar / University of Bologna / Reproductive Technologies Laboratory / /

IndustryTerm

biotechnology / predetermined genomic site / gene conversion accounting / investigator-selected chromosomal site / target site / production / cleavage site / restriction site / individual site / /

MedicalCondition

X-linked SCID / CD40 ligand deficiency / HIV / human severe combined immunodeficiency / X-linked severe combined immunodeficiency / osteogenesis imperfecta / X-linked chronic granulomatous disease / leukemia / severe combined immunodeficiency / West Nile virus infection / lentiviral infection / SCID / infection / therapeutic gene causing lymphoma / human disease / /

MedicalTreatment

antibiotics / gene therapy / /

Organization

1San Raffaele Telethon Institute for Gene Therapy / Harvard Stem Cell Institute / Nobel Committee / University of Bologna / Richmond Tech Center / Ethical Committee of the Reproductive Technologies Laboratory / National Park Service / H. San Raffaele Bioethical Committee / European Science Foundation / European Union / Centre de Recherche / /

Person

Edward Rebar / Anna Zingale / Adam Waite / Lucia Sergi Sergi / Igor Rupniewski / Sean Brennan / Aleida Perez / Russell DeKelver / Nat / Gene Ther / Bernhard Gentner / Midi Kit / Alessandro Aiuti / Deng Xia / Anna Lam / Dmitry Guschin / Jeffrey Miller / Jianbin Wang / Sarah Hinkley / Rosa Bacchetta / Giovanna Lazzari / Chamberlain / Brian Brown / Vita Salute San Raffaele / Yanhong Kong / Victor Bartsevich / Lei Zhang / /

Position

RT / Representative confocal analysis / amplification products representative / Fisher / representative / reporter / Marshall / G.P. / /

Product

CCR5 / Sigma / mitomycin / ImageQuant TL software / ZFNs / Shure E2c Headphone/Headset / integrase / Christian / Pietro Genovese1 / 2 / ImageQuant TL / thirdgeneration / lentiviral vector delivery Angelo Lombardo1 / 2 / GFP gene / lentiviral vectors / /

ProvinceOrState

Quebec / New Brunswick / South Carolina / California / /

PublishedMedium

NATURE BIOTECHNOLOGY / /

Region

West Nile / /

Technology

antibodies / BIOTECHNOLOGY / stem cells / HTML / human genome / gene therapy / gene expression / gene targeting / gene delivery / genotype / cell assays / recombination / /

URL

http /

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