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Histopathology / End point of clinical trials / Response Evaluation Criteria in Solid Tumors / Vismodegib / Medicine / Basal-cell carcinoma / Carcinoma


Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma (BCC): 24-month update of the pivotal ERIVANCE BCC study A Sekulic,1 MR Migden,2 AE Oro,3 L Dirix,4 K Lewis,5 JD Hainsworth,6
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Document Date: 2014-05-12 19:51:02


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Denver / South San Francisco / Orlando / Antwerp / Houston / Nashville / Essen / /

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F. Hoffmann-La Roche Ltd. / Chugai Pharmaceuticals / Curis Inc. / Eastern Cooperative Oncology Group / 10Genentech Inc. / Genentech / /

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Germany / Belgium / Japan / United States / Korea / /

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Business Partnership / Product Issues / Product Recall / /

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Colorado Cancer Center / Cannon Research Institute / 11University Hospital / Augustinus Hospital / Texas MD Anderson Cancer Center / University School / /

MedicalCondition

bRadiographically measurable disease / tumor / Basal cell carcinoma / measurable disease / disease / nodal metastases / Solid Tumors / Progressive disease / recurrences Significant morbidity/deformity / advanced basal cell carcinoma / deformity / Stable disease / /

MedicalTreatment

radiation therapy / radiotherapy / surgery / /

Organization

3Stanford University School of Medicine / Colorado Cancer Center / 4Sint-Augustinus Hospital / US Food and Drug Administration / 6Sarah Cannon Research Institute / FDA / 11University Hospital Essen / Stanford / /

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Hou / /

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investigator / driver / LoRusso PM / independent pathologist / Physician / /

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study / /

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Texas / Nebraska / Illinois / /

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Central Florida / /

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radiation / /

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