PHARMACOLOGY B TNFR2 Ab / Leinco Technologies / Becton Dickinson / Brooks SA / Prodo Labs / MRI Analysis Group / /
Country
United States / / /
Event
FDA Phase / Product Issues / /
Facility
University of British Columbia / Massachusetts General Hospital / University School / /
IndustryTerm
protein processing / cancer therapy / transient noncumulative apoptotic product / direct and indirect proteasome processing / Prevention of diabetes / antigen processing genes / intracellular machinery / treatment for several autoimmune (AI) diseases / therapy for cancer / chemicals / /
MedicalCondition
autoimmune diabetes / human tumor necrosis / systemic lupus erythematosus / celiac disease / insulin-dependent diabetes mellitus / tumour necrosis / rheumatoid arthritis / spontaneous diabetes / AI diseases / several AI diseases / Sjogren’s syndrome / multiple sclerosis / human diabetes / Demyelination / psoriasis / Graves’ disease / MS / lupus / both diseases / I diabetes / human AI diseases / diverse AI diseases / autoimmune disorders / late-stage AI disease / onset AI diseases / necrosis / cancer / kDa tumor necrosis / disease / hypothyroidism / human AI disease / Crohn’s disease / diabetes / thereby hampering disease / ulcerative colitis / tumor necrosis / AI disease / systemic lupus / autoimmune disease / diseases / each disease / chronic diseases / antitumor necrosis / inflammation / /
MedicalTreatment
immunotherapy / cancer therapy / immunosuppression / /
Organization
Harvard Medical School / Massachusetts General Hospital / National Academy of Sciences / Association of LMP2 and LMP7 / Denise L. Faustman‡ Department of Immunobiology / Washington University School of Medicine / Iacocca Foundation / University of British Columbia / /
Person
Douglas Burger / Ig / M. Davis / Denise L. Faustman / L. Murphy / Jack Zhang / Philip Needleman / Ann Rheum / /
Position
representative / Ficoll Author / /
Product
Remicade / CD8 / major histocompatibility complex class / TNF / cells / /
Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism Liqin Ban, Jack Zhang, Limei Wang, Willem Kuhtreiber†, Douglas Burger, and Denise L. Faustman‡ Department of Immunobiology, M