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Amides / Biomolecules / Lipids / Palmitoylethanolamide / Non-steroidal anti-inflammatory drugs / Progestagens / Carrageenan / Progesterone / Hyperalgesia / Chemistry / Endocrine system / Biology


The NAMPT inhibitor FK866 reverts the damage in spinal cord injury
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City

Ann Arbor / Santa Clara / Nicosia / Malvern / Stansted / Castellheim / Comerio / Bristol / Manchester / Oberkochen / Nossan / Thetford / /

Company

Carl Zeiss SMT AG / Agilent Technologies / Sigma-Aldrich / LJ Pharma / Epitech Group / Creative Commons / BioMed Central Ltd. / Int J Pharm / Diebold / JP Russell Science Ltd / /

Country

Germany / Netherlands / Italy / Cyprus / United States / United Kingdom / /

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Event

FDA Phase / /

Facility

University of Manchester / Manchester Royal Infirmary / University of Messina / Manchester Biomedical Research Centre / University of Messina Review Board / /

IndustryTerm

pharmaceutical field / peripheral and central nervous systems / energy / active pharmaceutical ingredient / chemical / soluble products / /

MedicalCondition

inflammatory response / Hyperalgesia / Discussion Nonresolving inflammation / Immune and inflammatory mechanisms / inflammatory processes / inflammatory process / chronic pain / carrageenan-induced inflammation / both inflammation / carrageenan-induced rat paw inflammation / inflammatory cells / neuropsychiatric disorders / subacute inflammatory response / organ dysfunction / inflammatory pain Daniela Impellizzeri1† / Inflammatory cell infiltration / sepsis / spinal cord injury / inflammatory pain / necrosis / cutaneous hyperalgesia / disease / psychiatric illness / ischaemia/reperfusion injury / acute inflammation / systemic inflammatory response syndrome / stroke / carrageenan-induced inflammatory pain / carrageenan-induced thermal hyperalgesia / pain / perispinal inflammation / inflammatory conditions / Parkinson’s disease / chronic disease / thermal hyperalgesia / neurodegenerative diseases / inflammation / rat arthritis / β-Amyloid-induced inflammation / Background Inflammation / /

MedicalTreatment

pharmacotherapy / /

Organization

University of Messina / Manchester Biomedical Research Centre / University of Manchester / Manchester / European Economic Community / Oral administration / Intraperitoneal administration / US Federal Reserve / Department of Biological and Environmental Sciences / /

Person

Ferdinando Stagno D’Alcontres / Arch Pharm Res / Giovanni Leotta / Baxter Healthcare / Ding / Nathan / Valentina Malvagni / /

Position

mediator / anti-inflammatory and neuroprotective lipid mediator / major driver / Major / representative / /

Product

Intraplantar injection / CAR injection / Nikon D50 Digital Camera / M-16 / acetic acid / felodipine / Nikon D90 Digital Camera / All / /

PublishedMedium

PLoS One / /

Technology

3g / /

URL

http /

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