pharmacokinetics

Results: 1088



#Item
751Biology / Enzymes / Pharmacokinetics / Enzyme inhibitors / Pharmacology / Enzyme / Microsome / Physiologically based pharmacokinetic modelling / Chemistry / Metabolism / Pharmaceutical sciences

Figure 3. General Scheme of Model-Based Prediction: The Investigational Drug (and Metabolite Present at ≥25% of Parent Drug AUC) as an Interacting Drug of CYP Enzymes CYP induction CYP inhibition (reversible and time-d

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Source URL: www.fda.gov

Language: English
752Toxicology / Pharmacokinetics / Pharmacy / Occupational safety and health / California Office of Environmental Health Hazard Assessment / Lead poisoning / Physiologically based pharmacokinetic modelling / Blood lead level / Inhalation exposure / Pharmaceutical sciences / Health / Pharmacology

Estimating Workplace Air and Worker Blood Lead Concentration using an Updated Physiologically-based Pharmacokinetic (PBPK) Model Office of Environmental Health Hazard Assessment (OEHHA) California Environmental Protectio

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Source URL: www.cdph.ca.gov

Language: English - Date: 2014-06-11 15:29:56
753Biomolecules / Catalysis / Pharmacokinetics / Metabolism / Enzyme / In vitro / In vivo / Cytochrome P450 / Simcyp Simulator / Chemistry / Pharmaceutical sciences / Pharmacology

Figure 1. Metabolism-Based Drug-Drug Interaction Studies — Decision Tree Conduct In Vitro Metabolism and Drug-Drug Interaction Studies in Human Tissuesa - Phase I enzymes: CYP 1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 3A, others

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Source URL: www.fda.gov

Language: English
754Decabromodiphenyl ether / Polybrominated diphenyl ethers / Octabromodiphenyl ether / Diphenyl ether / Biomonitoring / ADME / Pharmacokinetics / Bromine / Ether / Chemistry / Flame retardants / Organobromides

VOLUNTARY CHILDRENS CHEMICAL EVALUATION

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Source URL: www.epa.gov

Language: English - Date: 2008-04-22 15:30:48
755Pharmacology / Medicine / Organochlorides / Pharmacokinetics / Pharmacy / Physiologically based pharmacokinetic modelling / Toxicity / Perfluorooctanoic acid / Ethyl carbamate / Toxicology / Chemistry / Pharmaceutical sciences

Microsoft Word - setzer-biosketch[removed]doc

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Source URL: epa.gov

Language: English - Date: 2012-06-05 10:31:44
756Science / Medicine / Pharmacology / Genomics / Toxicogenomics / Pharmacokinetics / Quantitative structure–activity relationship / ADME / Medicinal chemistry / Toxicology / Chemistry

Microsoft Word - Biosketch AMRichard 05Aug2009.doc

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Source URL: epa.gov

Language: English - Date: 2012-06-05 10:31:37
757Lactams / Pharmacokinetics / Nitrazepam / Hepatotoxicity / Simcyp Simulator / Ezetimibe / Chemistry / Organic chemistry / Medicine

Guidance for Industry Pharmacokinetics in Patients with Impaired Hepatic Function: Study Design, Data Analysis, and Impact on Dosing and Labeling

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Source URL: www.fda.gov

Language: English - Date: 2003-05-29 13:23:10
758Medicine / Kidney diseases / Pharmacokinetics / Chronic kidney disease / Organ failure / Adverse drug reaction / Pharmaceutical sciences / Pharmacology / Pharmacy

Clinical Pharmacology AC meeting

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Source URL: www.fda.gov

Language: English
759Pharmacokinetics / Pharmacy / Organochlorides / Amides / Physiologically based pharmacokinetic modelling / Ketoconazole / Alprazolam / Pharmaceutical sciences / Pharmacology / Chemistry

International Conference on Drug Development

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Source URL: www.fda.gov

Language: English
760Pharmacokinetics / Anticoagulants / Pharmacy / Morpholines / Rivaroxaban / Physiologically based pharmacokinetic modelling / Ketoconazole / Direct Xa inhibitor / Clearance / Pharmacology / Pharmaceutical sciences / Chemistry

Microsoft PowerPoint - 12MAR2010_ASCPT_rivaroxaban.ppt

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Source URL: www.fda.gov

Language: English
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