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Study of the correlation of baseline biomarkers and DNA demethylation to clinical responses in a phase 1/2, randomized study of SGI-110, a novel subcutaneous hypomethylating agent in the treatment of relapsed/refractory
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City

Buffalo / Houston / Amsterdam / Toronto / Raleigh / New York / Chicago / Intermediate / /

Company

Astex Pharmaceuticals Inc. / Johnson and Johnson / Celgene / Incyte / /

Event

FDA Phase / /

Facility

Mohammad Azab10 Fels Institute / Temple University / University of Southern California / MD Anderson Cancer Center / University of Texas / Princess Margaret Hospital / Roswell Park Cancer Institute / Weill Cornell Medical College / University of Chicago Medical Center / Duke University Medical Center / /

IndustryTerm

treatment of relapsed/refractory acute myeloid leukemia / /

MedicalCondition

Cancer / Leukopenia / Neutropenia / Nausea / Thrombocytopenia / pain / Vomiting / Fatigue / Diarrhea / Cough / Anemia / /

Organization

Congress / Princess Margaret Hospital / University of Southern California / Los Angeles / Mohammad Azab10 Fels Institute / Temple University / Philadelphia / Weill Cornell Medical College / Duke University Medical Center / Roswell Park Cancer Institute / USC Keck School of Medicine / University of Chicago Medical Center / University of Texas / /

Person

Jean Pierre / Karen Yee / Jean Pierre Issa / Elizabeth Griffiths / Gail Roboz / Mohammad Azab / Lisa Chen / Raoul Tibes / Mayo Clinic Arizona / David Rizzieri / Wendy Stock / /

Product

SC / SGI-110 / /

ProvinceOrState

Texas / Southern California / New York / /

Region

Southern California / /

Technology

gene expression / Transplantation / /

SocialTag