SAMHSA Opioid Overdose Toolkit

Source URL: atf3.clincocommunicat.netdna-cdn.com

• Ketones
• Alcohols
• Euphoriants
• Phenols
• Naloxone
• Buprenorphine
• Opioid dependence
• Methadone
• Opioid antagonist
• Chemistry
• Organic chemistry
• Morphinans

Strain Stimulus Time (min) Replicates Used for diff exp test Used for clustering Used for TLC analysis Atf3(-/-) unstimulated 0 3 x x Atf3(-/-) CpG 60 1 x x Atf3(-/-) CpG 120 1

Source URL: www.ncbi.nlm.nih.gov

Type Identifier Source mouse strain Atf3[removed]MGI:[removed]) Dr. Tsonwin Hai, Ohio State University, Columbus, OH, USA mouse strain Crem[removed]MGI:[removed]) Dr. Günther Schütz, German Cancer Research Center, Heidelberg,

Source URL: www.ncbi.nlm.nih.gov

• Animal testing
• C57BL/6
• C57
• MYD88
• Real-time polymerase chain reaction
• IRF1
• Biology
• Mice
• Laboratory techniques

Genotype Protein Gene title Protein function and relevance Atf3[removed]] ATF3 activating transcription factor 3 transcription factor; negative regulator of TLR4 response [6] Crem[removed]] CREM cAMP responsive element m

Source URL: www.ncbi.nlm.nih.gov

Symbol GeneID Probeset Cluster TRANSFAC matrices Ahr 11622 1422631_at 11 AHRARNT_01, AHRARNT_02, AHRHIF_Q6, AHR_01, AHR_Q5 Atf1 11908 1417296_at 14 ATF1_Q6, CREBATF_Q6, CREB_Q3 Atf3 11910 1449363_at 25 ATF3_Q6, CREBATF_Q

Source URL: www.ncbi.nlm.nih.gov

• IRF7
• IRF3
• NFAT
• STAT1
• FOXM1
• FOX proteins
• RFX5
• IRF5
• HMGA2
• Transcription factors
• Biology
• IRF2

16 (2), 2013 l DOI: [removed]bjmg[removed]

Source URL: www.ncbi.nlm.nih.gov

• Activating transcription factor
• C-jun
• FOSB
• ATF3
• Hox gene
• SRD5A2
• Kruppel-like factors
• BTG2
• Biology
• Transcription factors
• Hypospadias