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Science / Protein folding / Biochemistry / Puzzle video games / Video games / Foldit / David Baker / Protein structure prediction / Energy minimization / Biology / Protein structure / Bioinformatics


Algorithm discovery by protein folding game players Firas Khatiba, Seth Cooperb, Michael D. Tykaa, Kefan Xub, Ilya Makedonb, Zoran Popovićb, David Bakera,c,1, and Foldit Players a Department of Biochemistry; bDepartment
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Document Date: 2011-12-08 12:00:18

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File Size: 2,39 MB

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City

Seattle / New York / Melville / /

Company

Adobe / Zoran / Microsoft / Foldit / /

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Event

Natural Disaster / /

Facility

Galaxy Zoo / Howard Hughes Medical Institute / cHoward Hughes Medical Institute / University of Washington / American Institute of Physics / /

IndustryTerm

energy optimization / much more complex algorithms / low energy / gradient-based energy minimization / enzyme design protocols / automated tools / optimization protocol / player-developed folding algorithms / lowest energy structure / energy minima / closest local energy minimum / side chain / rubber bands / energy / rubber band constraints / recipe creation tool / fewer rubber bands / problem-informed search / online gamers / average energy / faster and more effective energy optimization / restrained energy minimization / online game / energy term / power tools / protein chain / side chains / low-energy solution / adding rubber bands / /

MusicGroup

Rubber / Rosetta / /

Organization

University of Washington / Defense Advanced Research Projects Agency / American Institute of Physics / National Science Foundation / cHoward Hughes Medical Institute / International Congress / Department of Biochemistry / National Aeronautics and Space Administration / Howard Hughes Medical Institute / Center for Game Science / /

Person

Ilya Makedonb / Rosetta Relax / Michael D. Tykaa / Steven Pletsch / David Baker / Blue Fuse / Grom / David Bakera / Firas Khatiba / Seth Cooperb / /

Position

author of Blue Fuse / Foldit player / recipe author / player / Author / Independently Developed Player and Scientist / /

Product

Foldit script interface / Foldit Players / /

ProvinceOrState

New York / Washington / South Carolina / /

Technology

three algorithms / enzyme design protocols / X-ray / unpublished Rosetta protocol / optimization protocol / Relax algorithm / Relax protocol / unpublished algorithm / machine learning / Foldit algorithms / Lua / two algorithms / player algorithm / Blue Fuse algorithm / Quake algorithm / Rosetta Relax protocols / http / simulation / Relax protocols / player-developed folding algorithms / Rosetta algorithms / GUI / Scientist Algorithms / using this initial GUI / /

URL

www.pnas.org/cgi/doi/10.1073/pnas.1115898108 / http /

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