Generation of mice with a conditional knockout of ROCK1 and ROCK2 using nuclease mediated gene targeting Rho GTPases are major regulators of the cytoskeleton and thus crucial for cell movement and the interaction of cell

Source URL: bmi.ku.dk

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Source URL: www.dot.ca.gov

PNAS PLUS Hypoxia-inducible factors mediate coordinated RhoAROCK1 expression and signaling in breast cancer cells Daniele M. Gilkesa,b,c, Lisha Xianga,b, Sun Joo Leea,b, Pallavi Chaturvedia,b, Maimon E. Hubbia,b, Denis

Source URL: web1.johnshopkins.edu

• Cell cycle
• Genes
• Transcription factors
• Hypoxia-inducible factors
• Rho-associated protein kinase
• RHOA
• Rho family of GTPases
• ROCK1
• Metastatic breast cancer
• Biology
• Cell biology
• Proteins